Table 1:
Risk Factors For the Development of Anaphylaxis
Risk Factor
Comment
Age Children: higher frequency of food-related anaphylaxis
Adults: higher frequency of anaphylaxis related to antibiotics, radiocontrast media, anesthetic agents, and insect stings
Gender Females: anaphylaxis to latex, aspirin, radiocontrast media, and muscle relaxants more frequent
Males: anaphylaxis to insect venom more frequent
Socioeconomic status Increased frequency of anaphylaxis with higher socioeconomic status
Route of administration Oral antigens less likely to trigger anaphylaxis than parenteral antigens.
Oral antigens less likely to trigger severe symptoms than parenteral antigens
Timing of administration Interrupted therapy more likely to predispose to anaphylaxis
Atopy Risk factor for both anaphylactic and anaphylactoid reactions
Exposure history The longer the interval since previous antigen exposure, the less likely a reaction will occur
  
Copyright 2004 The Cleveland Clinic Foundation

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