| Table 1: | |
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Risk
Factors For the Development of Anaphylaxis
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Risk
Factor
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Comment
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| Age | Children:
higher frequency of food-related anaphylaxis Adults: higher frequency of anaphylaxis related to antibiotics, radiocontrast media, anesthetic agents, and insect stings |
| Gender | Females:
anaphylaxis to latex, aspirin, radiocontrast media, and muscle relaxants
more frequent Males: anaphylaxis to insect venom more frequent |
| Socioeconomic status | Increased frequency of anaphylaxis with higher socioeconomic status |
| Route of administration | Oral
antigens less likely to trigger anaphylaxis than parenteral antigens. Oral antigens less likely to trigger severe symptoms than parenteral antigens |
| Timing of administration | Interrupted therapy more likely to predispose to anaphylaxis |
| Atopy | Risk factor for both anaphylactic and anaphylactoid reactions |
| Exposure history | The longer the interval since previous antigen exposure, the less likely a reaction will occur |
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Copyright
2004 The Cleveland Clinic Foundation
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