Table 6:
Fibrinolytic Therapy for Myocardial Infarction
Agent
Trade
Name
Dosing
Patency @
90 minutes
Alteplase
Activase
Body weight > 67 kg
15 mg load + 50 mg/30 min + 35 mg/60 min intravenously
Body weight < 67 kg
15 mg load + 0.75 mg/kg/30 min (< 50 mg total) +
0.5 mg/kg/60 min (< 35 mg total)
75%
Reteplase
Retavase
10 units/2 minutes + wait 30 minutes + 10 units/2 minutes intravenously
75%
Streptokinase
Streptase
1.5 million units/60 minutes intravenously
50%
  
Copyright 2002 The Cleveland Clinic Foundation

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