Table 5:
Predictors of Poor Outcome in Dilated Cardiomyopathy
Test
Features
Clinical Increased age, male gender, ischemic heart disease, diabetes, syncope, right heart failure symptoms, symptomatic ventricular arrhythmias, persistent gallop rhythm, persistent jugular venous distention, systemic hypotension, peripheral vascular disease
Laboratory Hyponatremia, persistently elevated B-type natriuretic peptide and A-type natriuretic peptide levels, elevated norepinephrine and renin levels
Electrocardiogram Left bundle branch block, first- and second-degree atrioventricular block
Echocardiogram Increased ventricular dimensions, reduced ejection fraction, restrictive diastolic filling pattern, severe mitral and/or tricuspid regurgitation
Chest radiograph Increased cardiothoracic ratio
Coronary angiography Multivessel obstructive disease
Hemodynamic data Pulmonary capillary wedge pressure >20 mm Hg, cardiac index <2.5 L/min/m2, pulmonary hypertension, elevated central venous pressure
Cardiopulmonary exercise test Maximal systemic oxygen uptake <12 mL/kg/min
Endomyocardial biopsy Loss of intracellular myofilaments
  
Copyright 2003 The Cleveland Clinic Foundation

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