Table 1:
Risk Factors for Venous Thromboembolic Disease
Stasis/
Endothelial Injury
Thrombophilias
Medical
Conditions
Drugs
Other
Indwelling
venous device
Activated protein C resistance

Malignancy
(Solid-tumor and myeloproliferative disorders)

Oral contraceptive use Increasing age
Surgery
(most commonly
pelvic and orthopedic)
Factor V Leiden Pregnancy Hormone replacement therapy
Major trauma, fracture Prothrombin gene mutation G20210A Myocardial infarction Chemotherapy (including tamoxifen)
Prolonged travel Hyperhomocysteinemia Congestive heart failure
Paralysis
(including anesthesia for > 30 min)
Anticardiolipin antibodies Stroke
Varicose veins Lupus anticoagulant Obesity
  Elevated factor VIII level Inflammatory bowel disease
  Protein C deficiency Nephrotic syndrome
  Protein S deficiency History of DVT
  Dysfibrinogenemia Heparin-induced thrombocytopenia
  Dysplasminogenemia Paroxysmal nocturnal hemoglobinuria    
  
Copyright 2002 The Cleveland Clinic Foundation

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