Table 1:
Complications of Chronic Pancreatitis
Complication
Signs and Symptoms
Treatment
Pseudocyst
  • Increased pain
  • Vomiting
  • Mild elevation in amylase and lipase

Drainage for large or symptomatic pseudocysts:

  • Endoscopic drainage
    (transmural or transpapillary)
  • Surgical drainage
    (cyst-gastrostomy or cyst-jejunostomy)
Biliary obstruction
  • Jaundice
  • Drainage of obstructing pseudocyst
  • Endoscopic decompression
  • Surgical decompression
Gastric outlet obstruction
  • Abdominal pain
  • Early satiety
  • Nausea and vomiting
  • Drainage of pseudocyst
  • Surgical gastrojejunostomy
Pancreatic adenocarcinoma
  • Increased pain
  • Weight loss
  • Consider surgical resection
  • Palliation
Pancreatic ascites
  • Increased abdominal girth
  • High amylase ascites
  • Endoscopic stent placement
  • Total parenteral nutrition
Pleural effusion
  • Shortness of breath
  • High amylase pleural fluid
  • Therapeutic thoracentesis
  • Endoscopic stent placement
  • Total parenteral nutrition
Splenic vein thrombosis
  • Bleeding from gastric
    varices
  • Splenectomy
 
Copyright 2005 The Cleveland Clinic Foundation

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