1. Patients with clinical manifestations compatible with HH
   a. Unexplained liver disease, hepatomegaly, or elevated liver enzymes
   b. Type II diabetes mellitus with associated liver disease, cardiomyopathy,
       or early-onset sexual dysfunction
   c. Early-onset arthropathy, cardiomyopathy, cardiac dysrhythmias. or sexual dysfunction
2. Patients without clinical manifestations of HH
   a. First-degree relatives of a patient with identified HH
   b. Incidental finding of elevated serum iron markers (eg, iron saturation or serum ferritin)
   c. Incidental finding of elevated liver enzymes or hepatomegaly, or a compatible CT
       or MRI of the liver