| Table 8: | ||
|
Contrasting
Features of Two Autoimmune Liver Diseases
|
||
|
Autoimmune
Chronic Hepatitis
|
Primary
Biliary
Cirrhosis |
|
| AST, ALT | 7 to 10 times upper limits of normal (ULN) | 1 to 3 times ULN |
| Alkaline phosphatase | 1 to 3 times ULN | 2 to 10 times ULN |
| Anti-smooth
muscle antibody positive |
90% (usually high titer) | 10%
to 20% (usually low titer) |
| Antimitochondrial antibody positive | 10-20%, (usually low titer) | 90-100% (usually in high titer) |
| Liver-kidney microsomal anitbody positive | Positive in some cases where smooth muscle antibody is negative (rare in North America) |
Negative
|
|
Copyright
2002 The Cleveland Clinic Foundation
|
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