Table 1:
Conditions associated with macrovesicular steatosis
  • NAFLD

  • Alcohol

  • Drugs
    – Estorgens
    – Coumadin
    – Tamoxifen
    – Valproic acid
    – Methotrexate
    – Isoniazid
    – Corticosteroids
    – Vitamin A
    – Troglitazone
    – L-Asparaginase
    – Amiodarone
    – Perhexilline
    – Calcium channel blockers
    – Nucleoside analogues
  • Hepatitis C (genotype 3)


  • Nutritional
    • - Rapid weight loss
    • - Total parenteral nutrition
  • Surgical
    • – Gastrointestinal surgery for obesity
    • – Extensive small-bowel resection

  • Metabolic disorders
    • - Cystic fibrosis
    • - Abetalipoproteinemia, etc

  • Syndromes associated with obesity/ insulin resistance
    • - Lipodystrophies
    • - Hypopituitarism
    • - Prader-Willi syndrome
Copyright 2006 The Cleveland Clinic Foundation

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