| Table 2: | |||
|
Methods
of Measuring Urinary Protein and Ranges of Abnormal Excretion
|
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|
Method
|
Normal
|
Microalbuminuria
|
Macroalbuminuria
|
| 24-hour urine collection |
<150
mg/day
|
150-300
mg/day
|
>300
mg/day
|
| Spot-protein-to-creatinine ratio (mg/mg)* |
<150
mg/day
Estimate 1 g creatinine excretion per 1.73 m2 (Ratio of 0.15 = 150 mg protein 24 hrs . 1.73 m2) Or estimate per 20 mg/kg creatinine excretion for men, 15 mg/kg for women |
150-300
mg 0.135-0.27 for 60-kg female
|
>300
mg
Ratio: >0.36 for 60-kg male >0.27 for 60-kg female |
| Albumin:creatinine ratio (µg/mg)† |
<30
µg/mg
|
30-300
µg/mg
|
>300 µg/mg |
| *
Good for screening; does not correlate well with 24 hour urinary protein
at higher (nephrotic) levels of proteinuria. † Good for screening; does not account for patient weight or muscle mass; some recommend ration of 17-249 µg/mg for women and 25-354 µg/mg for men to define microalbuminuria. |
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Copyright
2003 The Cleveland Clinic Foundation
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