| Table 2: | |||
|
Percent
of the Usual Recommended Dose of Antihypertensive Medication
|
|||
|
Antihypertensive
Agents |
Chronic
Kidney Disease
|
||
|
Stage
1 and 2
|
Stage
3 and 4
|
Stage
5
|
|
|
Diuretics
|
|||
| Bumetanide |
100%‡
|
100%
|
100%
|
| Chlorthalidone |
100%
|
Not
advised
|
AVOID
|
| Chlorthiazide |
100%
|
Not
advised
|
AVOID
|
| Furosemide |
100%
|
100%
|
100%
|
| Hydrochlorothiazide |
100%
|
Not
advised
|
AVOID
|
| Indapamide |
100%
|
Not
advised
|
AVOID
|
| Metolazone |
100%
|
100%
|
100%
|
| Torsemide |
100%
|
100%
|
100%
|
|
Beta-Adrenergic
Blockers
|
|||
| Acebutolol |
100%
|
50%
|
30-50%
|
| Atenolol |
100%
|
50%
|
25-50%
|
| Betaxolol |
100%
|
100%
|
50%
|
| Bisoprolol |
100%
|
50%
|
25%
|
| Carteolol |
100%
|
50%
|
25%
|
| Carvedilol |
100%
|
100%
|
100%
|
| Labetalol |
100%
|
100%
|
100%
|
| Metoprolol |
100%
|
100%
|
100%
|
| Nadolol |
100%
|
50%
|
25%
|
| Penbutolol |
100%
|
100%
|
50%
|
| Pindolol |
100%
|
100%
|
50%
|
| Propranolol |
100%
|
100%
|
50%
|
| Timolol |
100%
|
100%
|
100%
|
|
Calcium
Channel Blockers
|
|||
| Amlodipine |
100%
|
100%
|
100%
|
| Diltiazem |
100%
|
100%
|
100%
|
| Felodipine |
100%
|
100%
|
100%
|
| Isradipine |
100%
|
100%
|
100%
|
| Nicardipine |
100%
|
100%
|
100%
|
| Nifedipine |
100%
|
100%
|
100%
|
| Nimodipine |
100%
|
100%
|
100%
|
| Nisoldipine |
100%
|
100%
|
100%
|
| Nitrendipine |
100%
|
100%
|
100%
|
| Verapamil |
100%
|
100%
|
100%
|
| Angiotensin Converting-Enzyme Inhibitors | |||
| Benazepril |
100%
|
75-100%
|
50-75%
|
| Captopril |
100%
|
75%
|
50%
|
| Enalapril |
100%
|
75-100%
|
50-75%
|
| Fosinopril |
100%
|
100%
|
100%
|
| Lisinopril |
100%
|
50-75%
|
25-50%
|
| Moesipril |
100%
|
50%
|
25%
|
| Quinapril |
100%
|
75-100%
|
50%
|
| Ramipril |
100%
|
50-75%
|
25-50%
|
| Trandropril |
100%
|
50%
|
25%
|
| Angiotensin II Receptor Antagonists | |||
| Candesartan |
100%
|
75-100%
|
50-75%
|
| Irbesartan |
100%
|
100%
|
100%
|
| Losartan |
100%
|
100%
|
100%
|
| Olmesartan |
100%
|
100%
|
100%
|
| Temisartan |
100%
|
100%
|
100%
|
| Valsartan |
100%
|
100%
|
100%
|
| Central Alpha Agonists | |||
| Clonidine |
100%
|
50%
|
25%
|
| Methyldopa |
100%
|
100%
|
50%
|
| Peripheral Alpha-1 Adrenergic Blockers | |||
| Doxazosin |
100%
|
100%
|
100%
|
| Prazosin |
100%
|
100%
|
100%
|
| Terazosin |
100%
|
100%
|
100%
|
| Direct Vasodilators | |||
| Hydralazine |
100%
|
100%
|
75%
|
| Minoxidil |
100%
|
100%
|
100%
|
| *
Listed in alphabetical order within classes, not preferential order. † Stages of chronic kidney disease, as defined by K/DOQI.5 ‡ % = percent of the usual recommended dose of antihypertensive medication |
|||
|
Copyright
2004 The Cleveland Clinic Foundation
|
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