| Table 1: | ||||||
|
Pathologic
Features of the Idiopathic Interstitial Pneumonias
|
||||||
|
Features
|
UIP
|
NSIP
|
BOOP
|
RB-ILD
|
DIP
|
LIP
|
| Temporal appearance |
Variegated
|
Uniform
|
Uniform
|
Uniform
|
Uniform
|
Uniform
|
| Spatial appearance |
Patchy
|
Uniform
|
Patchy
|
Patchy
|
Uniform
|
Patchy
|
| Interstitial inflammation |
Scant
|
Prominent
|
Mild
|
Mild-moderate
|
Rare
|
Alveolar
septal T-cells
|
| Collagen fibrosis |
Always,
patchy |
Variable,
diffuse |
Occasional
|
Variable,
peribronchiolar |
Rare
|
Rare
|
| Fibroblast proliferation |
Prominent
|
Rare,
diffuse |
No
|
No
|
No
|
No
|
| Organizing Pneumonitis |
No
|
Variable
|
Yes
|
No
|
No
|
No
|
| Microscopic honeycombing |
Yes
|
Rare
|
Rare
|
No
|
No
|
No
|
| Macrophage accumulation |
Variable
|
Variable
|
No
|
Peribronchiolar,
pigmented |
Alveolar,
non-pigmented |
No
|
|
Copyright
2002 The Cleveland Clinic Foundation
|
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