Table 4:
Options for the Treatment of Lung Cancer
Non-Small Cell

     Stage IA, IB, IIA, IIB

  • Surgical resection is the standard of care if patient deemed able to tolerate
  • Limited resection if patient is unable to tolerate larger resection
  • Radiotherapy if patient is unable to tolerate or chooses not to undergo resection
  • Adjuvant radiotherapy possibly of use if incomplete resection has occurred
  • Consider adjuvant chemotherapy

     Stage IIIA

  • Concurrent chemoradiotherapy using a platinum-based regimen if performance status is reasonable
  • Induction chemoradiotherapy followed by resection in selected patients, ideally as part of a study protocol

     Stage IIIB

  • Concurrent chemoradiotherapy using a platinum-based regimen if performance status is reasonable
  • Induction chemoradiotherapy followed by resection in highly selected patients, only as part of a study protocol

     Stage IV

  • Platinum-based chemotherapy regimen in patients with adequate performance status
Small Cell

     Limited-Stage

  • Combination chemotherapy with concurrent hyperfractionated radiotherapy if performance status is adequate
  • Prophylactic cranial radiation for those with a complete response to chemoradiotherapy

     Extensive-Stage

  • Combination chemotherapy if performance status is adequate
  
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