Table 4:
Comparison of Clinical and Diagnostic Characteristics of Benign Angiopathy of the
Central Nervous System and Granulomatous Angiitis of the Central Nervous System
  
BACNS
GACNS
Patients
Female-predominant
Male-predominant
Disease onset
Acute
Chronic
Clinical course
Monophasic
Recurrent
CSF findings
Normal
Abnormal
Abnormal angiography
100%
15%
Diagnostic modality
Angiography
CNS biopsy
Treatment
GC and Ca-Blockers
GC and CYC
Outcomes
Excellent*
Good†
CSF = cerebrospinal fluid; CNS = central nervous system; GC = glucocorticoids; CYC = cyclophosphamide; Ca-Blockers = calcium channel blockers
* 100% of BACNS patients had mild to no disability on the Barthel Index15 at follow-up
† 86% of GACNS patients showed mild to no disability and 14% moderate to severe disability on the Barthel Index15 at follow-up
Copyright 2004 The Cleveland Clinic Foundation

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