Table 3:
Clinical and Biochemical Manifestations of Polycystic Ovary Syndrome*
Clinical
  • Infertility
  • Menstrual disorder
  • Obesity
  • Androgen excess
  • Acanthosis nigricans
Biochemical
  • Elevated serum androgens (testosterone, androstenedione, DHEAS)
  • Decreased sex hormone binding globulin
  • Insulin resistance (abnormal fasting glucose/insulin ratio)
  • Abnormal leutinizing hormone (LH)/follicle stimulating hormone (FSH) ratio
  • Abnormal lipoprotein profile (increased triglycerides, low-density lipoprotein cholesterol and total cholesterol; decreased high-density lipoprotein cholesterol)
  • Mildly elevated prolactin
Imaging Studies
  • Ultrasound appearance of polycystic ovarian syndrome (PCOS)
* Not present in all patients
Copyright 2002 The Cleveland Clinic Foundation

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