| Table 1: | ||
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World
Health Organization Classification of Cardiomyopathies
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Cardiomyopathy
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Definition
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Sample
Etiologies
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| Dilated | Dilated left/both ventricle(s) with impaired contraction | Ischemic, idiopathic, familial/genetic, immune, alcoholic, toxic, valvular |
| Hypertrophic | Left and/or right ventricular hypertrophy | Familial with autosomal dominant inheritance (see chapter on Hypertrophic Cardiomyopathy) |
| Restrictive | Restrictive filling and reduced diastolic filling of one/both ventricles. Normal/near normal systolic function | Idiopathic, amyloidosis, endomyocardial fibrosis |
| Arrhythmogenic right ventricular cardiomyopathy | Fibro-fatty replacement of right ventricular myocardium,Uhl's anomaly ("parchment heart") | Unknown. Familial, usually autosomal dominant inheritance, with incomplete penetrance. Autosomal recessive inheritance may also occur. Rare forms associated with typical phenotype, eg, Naxos disease. |
| Unclassified | Not typical for previous 4 groups | Fibroelastosis, noncompacted myocardium, systolic dysfunction with minimal dilatation, mitochondrial diseases |
| Adapted from reference 1. | ||
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Copyright
2003 The Cleveland Clinic Foundation
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