Table 1:
World Health Organization Classification of Cardiomyopathies
Cardiomyopathy
Definition
Sample Etiologies
Dilated Dilated left/both ventricle(s) with impaired contraction Ischemic, idiopathic, familial/genetic, immune, alcoholic, toxic, valvular
Hypertrophic Left and/or right ventricular hypertrophy Familial with autosomal dominant inheritance (see chapter on Hypertrophic Cardiomyopathy)
Restrictive Restrictive filling and reduced diastolic filling of one/both ventricles. Normal/near normal systolic function Idiopathic, amyloidosis, endomyocardial fibrosis
Arrhythmogenic right ventricular cardiomyopathy Fibro-fatty replacement of right ventricular myocardium,Uhl's anomaly ("parchment heart") Unknown. Familial, usually autosomal dominant inheritance, with incomplete penetrance. Autosomal recessive inheritance may also occur. Rare forms associated with typical phenotype, eg, Naxos disease.
Unclassified Not typical for previous 4 groups Fibroelastosis, noncompacted myocardium, systolic dysfunction with minimal dilatation, mitochondrial diseases
Adapted from reference 1.
Copyright 2003 The Cleveland Clinic Foundation

Return to Cardiomyopathies Chapter