Table 2:
Secondary (Hypogonadotropic) Hypogonadism:
Major Causes
  • Pubertal delay
  • Hypogonadotropism
    • Congenital or acquired
    • Isolated or combined pituitary disease
    • Space-occupying lesions of pituitary/hypothalamus
    • Hyperprolactinemia per se
    • Infiltrative/infectious
    • Suppression:
      • Sex steroids
      • Gonadotropin-releasing hormone analogues
  • Aging?
Copyright 2005 The Cleveland Clinic Foundation

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