Table 1:
Relationship Among Hypothalamic, Pituitary, Target Glands, and Feedback Hormones
Hypothalamic
Regulatory Hormone
Pituitary
Hormone
Target
Gland
Feedback
Hormone
TRH
TSH
Thyroid gland
T4, T3
LH-RH
LH
Gonad
E2, T
LH-RH
FSH
Gonad
Inhibin, E2, T
GH-RH, SMS
GH
Multi-organs
IGF-1
PIF
Prolactin
Breast
?
CRH, ADH
ACTH
Adrenal
Cortisol
ACTH = Adrenocorticotropin hormone; ADH = Antidiuretic hormone; CRH = Corticotropin-releasing hormone; E2 = Estradiol; FSH = Follicle-stimulating hormone; GH = Growth hormone; GH-RH = Growth hormone-releasing hormone; IGF = Insulin-like growth factor; LH = Luteinizing hormone; LH-RH = Luteinizing hormone-releasing hormone; PIF = Prolactin release-inhibitory factor; SMS = Somatostatin; T = Testosterone; T4 = Thyroxine; TRH = Thyrotropin-releasing hormone; TSH = thyroid-stimulating hormone
Copyright 2002 The Cleveland Clinic Foundation

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