Table 2:
Signs and Symptoms of Wilson's Disease
Asymptomatic
Symptomatic
  • Biochemical abnormalities alone
  • Biochemical abnormalities and Kayser-Fleischer rings
  • Hepatic disease
    • Chronic active hepatitis
    • Cirrhosis
    • Fulminant hepatitis
  • Neurologic disease
    • Dystonia, dysarthria, tremors, involuntary choreiform movements—eg, features of cerebellar or extrapyramidal disease
  • Psychiatric disease, particularly with associated organic neurologic disease
  • Renal disease
    • Aminoaciduria, nephrocalcinosis
  • Arthropathy with osteochondritis dissecans
  • Opthalmologic manifestations
    • Kayser-Fleischer rings, sunflower cataracts
  • Hematologic manifestations
    • Hemolysis
 
Copyright 2002 The Cleveland Clinic Foundation

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