| Table 3: | ||
|
Diagnostic
Tests for Wilson's Disease
|
||
|
Level
1 Tests
|
Level
2 Tests
|
Level
3 Tests
|
| Low
serum ceruloplasmin (< 20 mg/dl) |
Liver histopathology and stainable copper | Ultrastructural study of hepatocytes |
| Kayser-Fleischer rings | Liver
copper concentration (more than 250 µg/g dry weight) |
Mutational gene analysis for Wilson's disease |
| Raised serum free copper (non-ceruloplasmin-bound) (more than 25 µg/dL) | Incorporation of radiocopper in to ceruloplasmin | |
| 24-hr urinary copper (more than 100 µg/24 hrs) | ||
| Adapted from reference 1. | ||
|
Copyright
2002 The Cleveland Clinic Foundation
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