| Table
4: |
|
Diagnostic
Criteria for Chronic Eosinophilic Leukemia
|
- Persistent
eosinophilia >1.5 x 109/L in blood, increased
bone marrow eosinophils
- >5% but
<19% myeloblasts in the bone marrow or >2% in the peripheral
blood
- Clonality
of myeloid cells
- No reactive
eosinophilia due to allergy, parasitic, infectious, pulmonary,
or collagen vascular disease
- No reactive
eosinophilia due to other malignancies:
- T-cell
lymphomas
- Acute
lymphoblastic leukemia/lymphoma
- Other
myeloproliferative diseases
- Acute
myeloid leukemia
- including
inv(16), t(16;16)
|
|
- No T-cell
population with abnormal cytokine production and aberrant phenotype
|
CML=Chronic
myelogenous leukemia
Adapted with permission from IARC Press (Reference 1). |
|