Table 1:
Prevalence of Major Hypercoagulable States in Different Patient Populations
Hypercoagulable
State
General
Population (%)
Patients with
Single VTE (%)
Thrombophilic
Families (%)
Factor V Leiden
3-7
20
50
Prothrombin G20210A
1-3
6
18
Antithrombin deficiency
0.02
1
4-8
Protein C deficiency
0.2-0.4
3
6-8
Protein S deficiency
N/A
1-2
3-13

Hyperhomocysteinemia
5-10
10-25
N/A
Antiphospholipid antibodies
0-7
5-15
N/A
N/A=not readily available or unknown.
Copyright 2003 The Cleveland Clinic Foundation

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