| Table 3: | |
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Unusual
Venous Thrombotic Presentations of Certain Hypercoagulable States
|
|
|
VTE
Presentation
|
Hypercoagulable
Condition
|
| Cerebral vein thrombosis | Prothrombin G20210A, antiphospholipid antibodies, antithrombin deficiency, essential thrombocythemia, paroxysmal nocturnal hemoglobinuria |
| Cerebral vein thrombosis in women using oral contraceptive pills | Prothrombin G20210A |
| Inferior vena cava, renal vein, mesenteric vein, portal and hepatic vein thrombosis | Antiphospholipid antibodies, cancer, antithrombin deficiency, myeloproliferative syndromes, paroxysmal nocturnal hemoglobinuria |
| Migratory superficial thrombophlebitis(Trousseau's syndrome) | Cancer (particularly adenocarcinoma of the gastrointestinal tract) |
| Recurrent superficial thrombophlebitis | Factor V Leiden, polycythemia vera, deficiencies of natural anticoagulants |
| Warfarin skin necrosis | Protein C and protein S deficiencies |
| Neonatal purpura fulminans | Homozygous protein C and protein S deficiencies |
| Unexplained fetal loss (three or more first-trimester miscarriages or one second- or third-trimester unexplained death of a morphologically normal fetus) | Antiphospholipid antibodies |
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Copyright
2003 The Cleveland Clinic Foundation
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