Table 3:
Unusual Venous Thrombotic Presentations of Certain Hypercoagulable States
VTE Presentation
Hypercoagulable Condition
Cerebral vein thrombosis Prothrombin G20210A, antiphospholipid antibodies, antithrombin deficiency, essential thrombocythemia, paroxysmal nocturnal hemoglobinuria
Cerebral vein thrombosis in women using oral contraceptive pills Prothrombin G20210A
Inferior vena cava, renal vein, mesenteric vein, portal and hepatic vein thrombosis Antiphospholipid antibodies, cancer, antithrombin deficiency, myeloproliferative syndromes, paroxysmal nocturnal hemoglobinuria
Migratory superficial thrombophlebitis(Trousseau's syndrome) Cancer (particularly adenocarcinoma of the gastrointestinal tract)
Recurrent superficial thrombophlebitis Factor V Leiden, polycythemia vera, deficiencies of natural anticoagulants
Warfarin skin necrosis Protein C and protein S deficiencies
Neonatal purpura fulminans Homozygous protein C and protein S deficiencies
Unexplained fetal loss (three or more first-trimester miscarriages or one second- or third-trimester unexplained death of a morphologically normal fetus) Antiphospholipid antibodies
  
Copyright 2003 The Cleveland Clinic Foundation

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