Table 2. Combination Therapy with Oral Antidiabetic Agents

Table 2. Combination Therapy with Oral Antidiabetic Agents

Combination	Additional Reduction in FPG (mg/dl)	Additional Reduction in Hemoglobin A_1c (%)
Glyburide/Acarbose	-34 compared to glyburide alone	-0.6 compared to glyburide alone
Sulfonylurea/Pioglitazone*	-58 compared to sulfonylurea alone	-1.3 compared to sulfonylurea alone
Sulfonylurea*/Rosiglitazoneˆ	-48 compared to sulfonylurea alone	-0.8 compared to sulfonylurea alone
Glyburide/Metformin	-63 compared to glyburide alone	-1.7 compared to glyburide alone
Metformin/Acarbose	-34 compared to metformin alone	-0.6 compared to metformin alone
Metformin/Pioglitazone**	-38 compared to metformin alone	-0.8 compared to metformin alone
Metformin/Rosiglitazoneˆ	-56 compared to metformin alone	-0.8 compared to metformin alone

*Sulfonylurea not specified;
**The dose used was 30 mg;
ˆ The dose used was 8 mg