Table 2. PROWESS Trial: Results

  
Xigris™
N
Deaths (%)
Placebo
N
Deaths (%)
Absolute Mortality Difference (%)
Relative Risk
(RR)
95% CI for RR
Overall
850
210 (25)
840
259 (31)
6
0.81
0.70-0.93
APACHE II quartile (score)
1st + 2nd (3-24)
436
82 (19)
437
83 (19)
0
0.99
0.75-1.30
3rd + 4th (25-53)
414
128 (31)
403
176 (44)
13
0.71
0.59-0.85
Adapted from the drotrecogin alfa product insert.

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