Table 2. PROWESS Trial: Results
|
Xigris™
N Deaths (%) |
Placebo
N Deaths (%) |
Absolute
Mortality Difference (%)
|
Relative
Risk
(RR) |
95%
CI for RR
|
|
| Overall |
850
210 (25) |
840
259 (31) |
6
|
0.81
|
0.70-0.93
|
| APACHE II quartile (score) | |||||
| 1st + 2nd (3-24) |
436
82 (19) |
437
83 (19) |
0
|
0.99
|
0.75-1.30
|
| 3rd + 4th (25-53) |
414
128 (31) |
403
176 (44) |
13
|
0.71
|
0.59-0.85
|