Table 2. PROWESS Trial:
Results
| Xigris™ N Deaths (%) |
Placebo N Deaths (%) |
Absolute Mortality Difference (%) | Relative
Risk (RR) |
95% CI for RR | |
|---|---|---|---|---|---|
| Overall | 850 210 (25) |
840 259 (31) |
6 | 0.81 | 0.70-0.93 |
| APACHE II quartile (score) | |||||
| 1st + 2nd (3-24) | 436 82 (19) |
437 83 (19) |
0 | 0.99 | 0.75-1.30 |
| 3rd + 4th (25-53) | 414 128 (31) |
403 176 (44) |
13 | 0.71 | 0.59-0.85 |
Adapted from the drotrecogin alfa product insert.