Table 3. Drug Interactions Reported in the Product Labeling of Various PPIs
| Drug |
|
|
|
|
|
| Drugs dependent on gastric pH for absorption* |
|
|
|
|
|
| Benzodiazepines |
|
|
|
|
|
| Cyclosporine |
|
|
|
|
|
| Diazepam |
|
|
|
|
|
| Digoxin |
|
|
|
|
|
| Disulfiram |
|
|
|
|
|
| Phenytoin |
|
|
|
|
|
| Theophylline |
|
|
|
|
|
| Warafin |
|
|
|
|
|
* = decreased absorption of drugs requiring acidic pH for absorption (eg, ketoconazole, ampicillin, iron)
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