Table 2. Interactions with Ephedra
Drugs
Lab Tests
Diseases or Conditions

Amitriptyline -
Blocks the hypertensive effects of ephedrine

- Norpseudoephedrine (Schedule IV) may be found in urine.

- May cause false-positives in urine and amphetamine and methamphetamine tests.

- May raise blood glucose levels.

 

Contraindicated



Angina
Anorexia
Bulimia
Cerebral insufficiency
Heart disease
Uncontrolled    hypertension
Hyperthyroid
Pheochromocytoma

 

 

 

 

Recommended against use



Anxiety
Benign prostatic hyperplasia
Diabetes
Essential tremor
Narrow-angle glaucoma
Hypertension
Kidney stones
Myasthenia gravis
Urinary retention

Caffeine -
Increases the risk of stimulatory adverse effects

Dexamethasone -
Ephedrine increases the clearance of dexamethasone
Antidiabetic Agents -
Ephedra can raise blood glucose levels

Digoxin -
Theoretically, combination can cause arrhythmias

Ergotamine -
Combination can cause hypertension

Monoamine Oxidase Inhibitors - Contraindicated due to risk of hypertensive crisis

Oxytocin -
May cause hypertension

Theophylline -
Increases the risk of stimulatory adverse effects

Urinary acidifiers -
Increases ephedrine excretion
Urinary alkalinizers -
Reduces ephedrine excretion

Click Here to Return to Article