Table 1. Characteristics of the Two Types of Heparin-Induced Thrombocytopenia
|
Characteristic |
Type
I |
Type
II |
| Frequency |
10
to 20 % |
1
to 3 % |
| Timing of onset |
2
to 3 days |
5
to 10 days |
| Nadir platelet count |
100,000/µl |
10,000
to 20,000/µl |
| Antibody mediated |
No |
Yes |
| Thromboembolic sequelae |
None |
30
to 80 % |
| Treatment |
Observe
Patient |
Discontinue
heparin by all routes, select other anticoagulation, adjunctive therapy |
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