Cardiovascular Disease
in Inflammatory Arthritis:
Getting to the Heart of the Matter

Patients with inflammatory arthritis are at increased risk for
cardiovascular disease. Studies have shown a clear link between inflammatory mediators and the development of cardiovascular disease, which has led to research on inhibiting the production of inflammatory cytokines. In clinical trials using TNF inhibitors, most data suggest that blocking TNF production can decrease the incidence of some cardiovascular events. However, TNF inhibitors have been associated with increases in other cardiovascular diseases, resulting in their contraindication in these patient populations. Clinical trials with investigational interleukin-receptor antagonists have shown positive results on some systemic inflammatory markers.

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	The Epidemiology of Increased Cardiovascular Death in Inflammatory Arthritis
	Estimated Time: 30 minutes Release Date: July 23, 2009 Type: Webcast	Technical Requirements: Windows Media Player Expiration Date: July 23, 2011 Specialties: Cardiology, Rheumatology
	Noninvasive Imaging for Early Cardiovascular Disease in Inflammatory Arthritis
	Estimated Time: 30 minutes Release Date: July 17, 2009 Type: Webcast	Technical Requirements: Windows Media Player Expiration Date: July 17, 2011 Specialties: Cardiology, Rheumatology
	Molecular Mechanism of Cardiovascular Disease in Inflammatory Arthritis
	Estimated Time: 15 minutes Release Date: September 10, 2009 Type: Webcast	Technical Requirements: Windows Media Player Expiration Date: September 10, 2011 Specialties: Cardiology, Rheumatology
	The Effect of Cytokines and Remittive Therapy for Inflammatory Arthritis on Cardiovascular Outcomes
	Estimated Time: 30 minutes Release Date: July 17, 2009 Type: Webcast	Technical Requirements: Windows Media Player Expiration Date: July 17, 2011 Specialties: Cardiology, Rheumatology
	Treatment Guidelines for Cardiovascular Disease in Inflammatory Arthritis
	Estimated Time: 30 minutes Release Date: July 17, 2009 Type: Webcast	Technical Requirements: Windows Media Player Expiration Date: July 17, 2011 Specialties: Cardiology, Rheumatology

Series Objectives

1. Review the epidemiology of increased cardiovascular morbidity and mortality associated with inflammatory arthritis.
2. Discuss how immune-mediated pathways in atherosclerosis may be associated with inflammatory arthritis.
3. Analyze emerging research on biomarkers being studied for cardiovascular disease in inflammatory arthritis.
4. Explain how cytokines and other therapies for inflammatory arthritis may affect the outcome of patients with inflammatory arthritis.
5. Recognize the need for early detection, risk stratification, and treatment guidelines for cardiovascular disease in inflammatory arthritis.
6. Describe state-of-the-art noninvasive imaging for early cardiovascular disease in inflammatory arthritis.

Target Audience

Rheumatologists, cardiologists, and other interested healthcare professionals.