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How to Obtain AMA PRA Category 1 Credit

  1. Read the CME Monograph.
  2. Complete the posttest (each question must be answered correctly).
  3. Log into your myCME account.
  4. Complete the credit and evaluation form.
  5. Print your personalized CME certificate.
  6. Credit can only be claimed once for this activity.

Biologic Therapies:
Optimizing Therapies
Online Monograph

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Release Date: October 29, 2015
Expiration Date: October 29, 2017

Estimated Time of Completion: 1 hour 30 minutes

Description

Biologic Therapies: Optimizing Therapies Online Monograph highlights the best practices for clinical practice. Throughout seven articles, expert faculty summarize treat to target therapy, bioengineering and biosimilars, connective tissue diseases and biologics, vaccines and biologics, and safety and comorbidity presentations from the recent Biologic Therapies VI Summit.

Learning Objectives

  1. Summarize the current knowledge of the biology and pathology of autoimmune and inflammatory disease.
  2. Describe the impact of bioengineering and biosimilars on biologic therapy efficacy, toxicity, and changing patterns of use.
  3. Critically appraise the "treat to target" philosophy and describe strategies to incorporate it into clinical practice.
  4. Summarize data on vaccine efficacy and safety and develop strategies to incorporate vaccines into clinical practice with the goal of enhancing the safety of biologic therapies.
  5. Critically assess clinical data on biologic use in the related specialties of dermatology, oncology, neurology, and gastroenterology; synthesize their insights on shared mechanisms and new pathways for different diseases to potential implications for rheumatology.
  6. Describe the efficacy and safety of biologic therapies and emerging new agents for systemic lupus erythematosus, Sjögren's syndrome, osteoporosis, vasculitis, and other disorders.
  7. Develop strategies for improving safety and increasing adherence when using biologics by appraising best practices of experts and engaging in interactive case discussions.

Target Audience

The online series is designed for rheumatologists, dermatologists, gastroenterologists, internal medicine and infectious disease physicians, cardiologists, pulmonologists, pediatricians, and associated allied health practitioners, including nurse practitioners, nurses, physician assistants interested in or using biologic therapeutics for autoimmune and inflammatory disorders.

Accreditation

The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Activity Directors and Faculty

Activity Directors

Leonard Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
R.J. Fasenmyer Chair of Clinical Immunology
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

M. Elaine Husni, MD, MPH
Director, Arthritis and Musculoskeletal Treatment Center
Vice Chair, Department of Rheumatic & Immunologic Diseases
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

Faculty

Carmen Gota, MD
Director of Fibromyalgia Clinic
Center for Vasculitis Care and Research
Department of Rheumatologic and Immunologic Diseases
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

Bochra Jandali, MD
University Hospitals
Cleveland, OH

Jonathan Kay, MD
Professor of Medicine
University of Massachusetts Medical School
Director of Clinical Research
Division of Rheumatology
UMass Memorial Medical Center
Worcester, MA

Elizabeth Kirchner, CNP
Department of Rheumatic and Immunologic Diseases
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

Gregg J. Silverman, MD
Co-Director, Musculoskeletal Center of Excellence
Professor of Medicine and Pathology
New York University School of Medicine
New York, NY

CME Disclaimer

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

Disclosures

In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they may have a relationship, which in the context of their presentations, could be perceived as a potential conflict of interest:

Leonard Calabrese, DO
  Abbvie, Inc.; Bristol Myers Squibb; Genentech/Roche; Janssen Scientific Affairs, LLC Consulting; Teaching and Speaking
  Crescendo Bioscience, Inc. Teaching and Speaking
  GSK; Pfizer; Inc., Sanofi Aventis; UCB, Inc. Consulting
 
Jonathan Kay, MD
  Abbvie, Inc.; Lilly; Pfizer, Inc. Consulting; Independent contractor (including contracted research)
  Alexion; Samsung Bioepis Membership on advisory committee or review panels
  Amgen; Astra Zeneca; Boehringer Ingelheim; Bristol-Myers Squibb Co.; Crescendo Bioscience, Inc.; Epirus Biopharaceuticals; Genentech; Hospira; Janssen; PanGenetics, B.V.; UCB Consulting
  Ardea Independent contractor (including contracted research)
  Roche Pharmaceuticals Independent contractor (including contracted research); Membership on advisory committee or review panels
 
Gregg J. Silverman, MD
  Genentech; Human Genome Sciences, Inc.; Pfizer; Roche Pharmaceuticals; Vertex Pharmaceuticals Consulting

The following faculty have indicated they have no relationship which, in the context of their presentations, could be perceived as a potential conflict of interest:

M. Elaine Husni, MD, MPH
Bochra Jandali, MD
Elizabeth Kirchner, CNP

All other planners, CME staff, and content reviewers, have no relevant financial relationships to disclose.

The Cleveland Clinic Foundation Center for Continuing Education acknowledges educational grants for partial support of this activity from:

Abbvie, Inc.
Bristol-Myers Squibb
Celgene Corporation
Crescendo Bioscience Inc.
Genentech, Inc.
Janssen Scientific Affairs, LLC
Pfizer
Questcor Pharmaceuticals, Inc.
UCB, Inc.

This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education and R.J. Fasenmyer Center for Clinical Immunology.