Biologic Therapies IV
Gout - Do Biologics
Make Sense?
Release Date: June 24, 2011
Expiration Date: June 24, 2013
Estimated Time of Completion: 30 minutes
Description
Biologic Therapies IV: Webcast Series is a compilation of live presentations recorded at the Biologic Therapies Summit IV: Current and Emerging Indications. This webcast series continues a successful tradition of presenting innovative, quality presentations that provide evidence-based, practical knowledge to fulfill participants' educational objectives. An international faculty of experts who span a multitude of scientific disciplines will provide their insights on a variety of timely topics, including the following:
- Research advances in immunodeficiencies and autoimmunity,
- Approved biologic agents and clinical trial data,
- Development of new biologic agents,
- Toxicities associated with biologic agents,
- Clinical implications and potential new indications.
Learning Objectives
- Discuss the intracellular mechanism by which monosodium urate crystals stimulate IL-1 beta production.
- Support the use of targeted biologic therapy to treat patients with acute gout who are intolerant of or unresponsive to NSAID and steroid therapy.
- Recognize major predictor of infusion reaction to pegloticase.
Target Audience
This activity is directed to rheumatologists, gastroenterologists, dermatologists, pulmonologists, internal medicine physicians, nurse practitioners, physician assistants, and other health care professionals interested in or using biologic therapies in autoimmune and inflammatory disorders.
Accreditation
The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The Cleveland Clinic Foundation Center for Continuing Education designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association Council on Continuing Medical Education for Category 2 credit.
Activity Director
Leonard Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University
Vice Chairman
Department of Rheumatic & Immunologic Diseases
R.J. Fasenmyer Chair of Clinical Immunology
Orthopaedic & Rheumatologic Institute
Cleveland Clinic
Cleveland, OH
Faculty
Brian Mandell, MD, PhD
Professor and Chairman, Department of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Editor-in-Chief, Cleveland Clinic Journal of Medicine
Center for Vasculitis Care and Research
Department of Rheumatic and Immunologic Diseases
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH
Disclosures
In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.
The following faculty have indicated that they may have a relationship which, in the context of their presentation, could be perceived as a potential conflict of interest:
| Leonard Calabrese, DO | ||
| Consulting: |
BMS; Elan Pharmaceuticals, Inc; Wyeth |
|
| Consulting, Teaching & Speaking: |
Abbott Laboratories; Amgen; Centocor; Genentech/Roche; Pfizer |
|
| Brian Mandell, MD, PhD | ||
| Consulting: |
URL Pharma |
|
| Consulting Independent contractor (including contracted research) : |
Savient; Takeda |
|
The Cleveland Clinic Foundation Center for Continuing Education acknowledges educational
grants for partial support of this activity from:
Abbott Laboratories Inc.,
Amgen, Inc.,
Bristol-Myers Squibb,
Centocor Ortho Biotech Services, LLC,
Genentech, Inc. and Biogen Idec,
UCB, Inc.
This CME activity was produced by The Cleveland Clinic Foundation Center for Continuing Education and the
R.J. Fasenmyer Center for Clinical Immunology.







