Webcast CME


E-Journal Club:
Advances in Therapy and Pathogenesis of Rheumatic Diseases

High Frequency of Anti-Drug Antibodies and
Association of Random Drug Levels with Efficacy
in Certolizumab Pegol Treated Patients with
Rheumatoid Arthritis

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Release Date:   March 3, 2017
Expiration Date:   March 3, 2018

Estimated Time of Completion:   30 minutes

Description

This EJournal Club series examines, discusses, and assesses of the most recent peer-reviewed literature on rheumatic diseases.

Dr. Leonard Calabrese will lead an interactive discussion with Dr. Meghna Jani of The University of Manchester. Together, they will review the article, "High Frequency of Anti-Drug Antibodies and Association of Random Drug Levels with Efficacy in Certolizumab Pegol Treated Patients with Rheumatoid Arthritis". Together they will filter, synthesize, and translate the key points into clinical pearls that can be applied to the clinician practice.

Learning Objectives

  1. Identify factors associated with immunogenicity to biologics.
  2. Describe the association of certolizumab drug levels, anti-drug antibodies and treatment response in rheumatoid arthritis.
  3. Highlight areas of future research and potential clinical implications.

Target Audience

This activity is intended for rheumatologists, immunologists, internal medicine practitioners and allied health professionals, including advanced practice clinicians and physician assistants who care for patients with immunologic diseases.

Accreditation

The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Activity Director and Faculty

Activity Director

Leonard Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
R.J. Fasenmyer Chair of Clinical Immunology
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

Faculty

Meghna Jani, MRCP, PhD
NIHR Clinical Lecturer
Centre for Musculoskeletal Research
The University of Manchester
Manchester, United Kingdom

CME Disclaimer

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

Disclosures

In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they have no relationship which, in the context of their presentation, could be perceived as a potential conflict of interest:

Leonard Calabrese, DO
Meghna Jani, MRCP, PhD

The Cleveland Clinic Foundation Center for Continuing Education acknowledges
an educational grant for support of this activity from
:
AbbVie Inc.
Celgene Corporation
Horizon Pharma USA, Inc.

This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education
and Cleveland Clinic's R.J. Fasenmyer Center for Clinical Immunology.