Webcast CME


E-Journal Club:
Advances in Therapy and Pathogenesis of Rheumatic Diseases

IgA Plasmablasts are Elevated in Subjects At Risk
for Future Rheumatoid Arthritis

 

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Release Date:   December 9, 2016
Expiration Date:   December 9, 2017

Estimated Time of Completion:   30 minutes

Description

This EJournal Club series will exam, discuss, and assess of the most recent peer-reviewed literature on rheumatic diseases. Dr. Leonard Calabrese will lead an interactive discussion with the Dr. Michael Holers of University of Colorado School of Medicine on the article, IgA Plasmablasts are Elevated in Subjects At Risk for Future Rheumatoid Arthritis. Together they will filter, synthesize, and translate the key points into clinical pearls that can be applied to the clinician practice.

Learning Objectives

  1. Describe the postulated role of the mucosal immune system in the initial development of antibodies to citrullinated protein/peptide antigens (ACPA).
  2. Explain the informative role of IgA ACPA in assessing how an individual initially develops immune alterations that lead to rheumatoid arthritis (RA) in the future.
  3. Develop an evaluation strategy for research subjects that would identify the mechanisms underlying the development of ACPA at mucosal sites in individuals who are at high risk for future RA.

Target Audience

This activity is intended for rheumatologists, immunologists, internal medicine practitioners and allied health professionals, including advanced practice clinicians and physician assistants who care for patients with immunologic diseases.

Accreditation

The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Activity Director and Faculty

Activity Director

Leonard Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
R.J. Fasenmyer Chair of Clinical Immunology
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

Faculty

V. Michael Holers, MD
Scoville Professor
Head, Division of Rheumatology
University of Colorado School of Medicine
Aurora, CO

CME Disclaimer

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

Disclosures

In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they have no relationship which, in the context of their presentation, could be perceived as a potential conflict of interest:

Leonard Calabrese, DO
V. Michael Holers, MD

The Cleveland Clinic Foundation Center for Continuing Education acknowledges
an educational grant for support of this activity from
:
AbbVie Inc.
Celgene Corporation
Horizon Pharma USA, Inc.

This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education
and Cleveland Clinic's R.J. Fasenmyer Center for Clinical Immunology.