Liver

Rheumatic Disease eJournal Club

Circulating Markers of Vascular Injury
and Angiogenesis in ANCA-Associated
Vasculitis

Publication:
Monach PA, Tomasson G, Specks U, et al. Arthritis Rheum. 2011;Sep 27.doi:10.1002/art.30615

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How to Obtain AMA PRA
Category 1 Credit

  1. Review the provided journal abstract and slides.
  2. Listen to the
    audio discussion.
  3. Complete the CME posttest (each question must be answered correctly).
  4. Login to your account.
  5. Complete the credit and evaluation form.
  6. Print your personalized
    CME certificate.

Technical Requirements

 

Release Date:   December 7, 2011
Expiration Date:
  December 7, 2012

Estimated Time of Completion:  30 minutes

Description
The purpose of this activity is to discuss a study that evaluates the value of circulating markers of vascular injury and angiogenesis in distinguishing active ANCA-associated vasculitis (AAV) from remission.

Learning Objectives

  1. Outline the design of a study assessing circulating markers of vascular injury and angiogenesis in patients with AAV.
  2. Describe how treatment affected these marker levels in patients with AAV.
  3. Discuss the relative value of these markers in distinguishing between active AAV and remission.

Target Audience
This activity is directed to rheumatologists, primary care physicians, and other clinicians who treat patients with rheumatic diseases, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), gout, systemic lupus erythematosus (SLE), and ANCA-associated vasculitis.

Accreditation
The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credits™.  Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association Council on Continuing Medical Education for Category 2 credit.

Activity Director

Leonard H. Calabrese, DO
Professor of Medicine
R.J. Fasenmyer Chair of Clinical Immunology
Vice Chairman
Department of Rheumatic and Immunologic Diseases
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Cleveland Clinic
Cleveland, Ohio

Faculty

Gary S. Hoffman, MD, MS
Professor of Medicine
Department of Vascular Care and Research
Cleveland Clinic Lerner College of Medicine
Harold C. Schott Chair for Rheumatic and Immunologic Diseases
Center for Vasculitis Care and Research
Cleveland Clinic
Cleveland, Ohio

Disclosure

In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty has indicated that he may have relationships which, in the context of his presentation, could be perceived as a potential conflict of interest:

  Leonard H. Calabrese, DO  
    Amgen Inc.; Bristol-Myers Squibb Company; Centocor, Inc.;
Pfizer Inc; Roche-Genentech
Consulting
       
    Amgen Inc.; Bristol-Myers Squibb Company; Centocor, Inc.;
Pfizer Inc; Roche-Genentech
Teaching and Speaking
     

The following faculty has indicated that he has no relationship which, in the context of his presentation, could be perceived as a potential conflict of interest:

Gary S. Hoffman, MD, MS

All other planners, CME staff, and content reviewers have no relevant financial relationships to disclose.

The Cleveland Clinic Foundation Center for Continuing Education
acknowledges an educational grant for support of this activity from Genentech, Inc.

This CME activity was produced by the Cleveland Clinic Center for Continuing Education
and
 

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