Table 1. FDA-approved
indications of the Proton Pump Inhibitors
| Indication | Esomeprazole (Nexium™) |
Lansoprazole (Prevacid®) |
Omeprazole (Prilosec™) |
Pantoprazole (Protonix®) |
Rabeprazole (Aciphex™) |
|---|---|---|---|---|---|
| Healing of erosive esophagitis | X | X | X | X | X |
| Maintenance of healed erosive esophagitis | X | X | X | X | X |
| Symptomatic
gastroesophageal reflux disease |
X | X | X | X | |
| Eradication of Heliobacter pylori infection | X | X | X | ||
| Prevention of NSAID-induced gastric ulcers | X | ||||
| Treatment of NSAID-induced gastric ulcers | X | ||||
| Healing of gastric ulcer | X | X | |||
| Healing of duodenal ulcer | X | X | X | ||
| Maintenance of duodenal ulcer | X | ||||
| Treatment of
pathological hypersecretory conditions (eg, Zollinger-Ellison Syndrome) |
X | X | X |
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