R J. Fasenmyer Center for Clinical Immunology presents
Cardiovascular Disease in Inflammatory Arthritis: Getting to the Heart of the Matter Symposium
May 6, 2009
InterContinental Hotel & Bank of America Conference Center
9801 Carnegie Avenue, Cleveland, Ohio

Description
Patients with inflammatory arthritis are at increased risk for cardiovascular disease. Studies have shown a clear link between inflammatory mediators and the development of cardiovascular disease, which has led to research on inhibiting the production of inflammatory cytokines. In clinical trials using TNF inhibitors, most data suggest that blocking TNF production can decrease the incidence of some cardiovascular events. However, TNF inhibitors have been associated with increases in other cardiovascular diseases, resulting in their contraindication in these patient populations. Clinical trials with investigational interleukin-receptor antagonists have shown positive results on some systemic inflammatory markers.
These research efforts have created a need for medical education providing evidence-based discussions of advances in cytokine inhibition and their effect on the care of patients with cardiovascular disease associated with inflammatory arthritis. This includes a review of the biologic mechanisms, potential therapeutic options for this patient population, risk-benefit ratios of each, and specific patient-selection criteria.
To address this educational need, the Cleveland Clinic Center for Continuing Education and the R.J. Fasenmyer Center for Clinical Immunology will present an evening symposium titled Cardiovascular Disease in Inflammatory Arthritis: Getting to the Heart of the Matter, on May 6, 2009, at the InterContinental Hotel and Bank of America Conference Center in Cleveland, Ohio. This educational activity is designed to increase practitioners’ knowledge of the biology and management strategies of cardiovascular disease associated with inflammatory arthritis, with the ultimate goal of improving the care of these patients.
Target Audience
Rheumatologists, cardiologists, and other interested healthcare professionals.
Learning Objectives
After completing these learning activities, the participant will be able to do the following:
- Review the epidemiology of increased cardiovascular morbidity and mortality associated with inflammatory arthritis;
- Discuss how immune-mediated pathways in atherosclerosis may be associated with inflammatory arthritis;
- Analyze emerging research on biomarkers being studied for cardiovascular disease in inflammatory arthritis;
- Explain how cytokines and other therapies for inflammatory arthritis may affect the outcome of patients with inflammatory arthritis;
- Recognize the need for early detection, risk stratification, and treatment guidelines for cardiovascular disease in inflammatory arthritis;
- Describe state-of-the-art noninvasive imaging for early cardiovascular disease in inflammatory arthritis.
Activity Directors
| Leonard Calabrese, DO Professor of Medicine Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Vice Chairman, Department of Rheumatic & Immunologic Diseases R.J. Fasenmyer Chair of Clinical Immunology Orthopaedic & Rheumatologic Institute Cleveland Clinic |
Elaine Husni, MD, MPH Assistant Professor Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Director, Clinical Outcomes Research Director, Arthritis and Musculoskeletal Treatment Center Department of Rheumatic & Immunologic Diseases Orthopaedic & Rheumatologic Institute Cleveland Clinic |
Faculty
| Joan M. Bathon, MD Professor of Medicine Deputy Director, Division of Rheumatology Director, The Johns Hopkins Arthritis Center Johns Hopkins University Baltimore, Maryland |
Steven Nissen, MD Chairman, Department of Cardiovascular Medicine Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University Director, Joseph J. Jacobs Center for Thrombosis and Vascular Biology Heart and Vascular Institute Cleveland Clinic Cleveland, Ohio |
| Stanley Hazen, MD, PhD Head of the Section for Preventive Cardiology and Rehabilitation Director for the Center for Cardiovascular Diagnostics and Prevention Departments of Cell Biology and Cardiovascular Medicine Cleveland Clinic Cleveland, Ohio |
Josef Smolen, MD Professor of Medicine and Chairman Division of Rheumatology Internal Medicine III Medical University of Vienna Vienna, Austria |
Agenda
| WEDNESDAY, MAY 6, 2009 | |
| 5:30 pm | Registration |
| 6:15 pm | Dinner |
| 6:55 pm | Introductions - Leonard Calabrese, DO |
| 7:00 pm | The Epidemiology of Increased Cardiovascular Death in Inflammatory Arthritis - Elaine Husni, MD |
| 7:20 pm | Noninvasive Imaging for Early Cardiovascular Disease in Inflammatory Arthritis - Steven Nissen, MD |
| 7:40 pm | Molecular Mechanism of Cardiovascular Disease in Inflammatory Arthritis - Stanley Hazen, MD, PhD |
| 8:00 pm | The Effect of Cytokines and Remittive Therapy for Inflammatory Arthritis on Cardiovascular Outcomes - Josef Smolen, MD |
| 8:20 pm | Treatment Guidelines for Cardiovascular Disease in Inflammatory Arthritis - Joan M. Bathon, MD |
| 8:40 pm | Panel Discussion & Questions |
| 9:00 pm | Adjourn |
Location
InterContinental Hotel and Bank of America Conference Center
9801 Carnegie Avenue
Cleveland, OH 44106
Phone: 216-707-4100 or 877-707-8999
Fax: 216-707-4101
Cleveland Clinic Map & Directions
Hotel Accommodations
A block of rooms has been reserved at the InterContinental Hotel until April 6, 2009. To make your reservations, contact the Hotel Reservations Department at 216-707-4100 or 1-877-707-8999. Please identify yourself as being with the Cleveland Clinic Biologic Therapies Summit & Cardiovascular Disease in Inflammatory Arthritis: Getting to the Heart of the Matter Symposium, (online code CM8) for a special rate of $169 single/double plus tax. The hotel and conference center is located on the campus of the Cleveland Clinic.
Ground Transportation
Taxi service is available from Cleveland Hopkins International Airport to the InterContinental Hotel and Bank of America Conference Center. As an alternative, take the rapid transit train from the airport to the Terminal Tower in downtown Cleveland and from there take a taxi to the InterContinental Hotel and Bank of America Conference Center.
Parking
Parking is available in the 100th Street Visitor’s Parking Garage. Valet parking is available at the hotel for an additional charge.
Additional Information
For more information about the course, contact UNITECH Communications®:
Local: 216.448.0770
Toll Free: 800.238.6750
Fax: 216.448.0784
For questions about registering online, call 216-448-0777 or email CMEregistration@ccf.org.
For emergency phone calls during the course, call 216-707-4100 and ask for the Cleveland Clinic Registration Desk.
Faculty Disclosure
The Cleveland Clinic Foundation Center for Continuing Education has implemented a policy to comply with the current Accreditation Council for Continuing Medical Education Standards for Commercial Support requiring resolution of all faculty conflicts of interest. Faculty declaring a relevant commercial interest will be identified in the activity syllabus.
Americans with Disabilities Act
The Cleveland Clinic Foundation Center for Continuing Education fully intends to comply with the legal requirements of the Americans with Disabilities act. If you need assistance, please notify UNITECH Communications® at 216.448.0770 or 800.238.6750 at least two weeks prior to the activity.
Accreditation
The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The Cleveland Clinic Foundation Center for Continuing Education designates this educational activity for a maximum of 2 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association Council on Continuing Medical Education for Category 2 credit.
The Ohio Board of Nursing will accept at face value the number of contact hours awarded for an educational activity that has been approved for CE by a nationally accredited system of CE approval. Therefore the 2 physician AMA PRA Category I Credits™ will be accepted for nursing credits. Nurses from other states should contact their State Board of Nursing.
If you're planning to attend this free event please consider attending its associated sister event: Biologic Therapies Summit III: |
Online Registration/Fees
Registration includes: syllabus and dinner.
| Category | Full Course |
|---|---|
| Physician | Complimentary |
| Resident / Fellow | Complimentary |
| Nurse | Complimentary |
| Nurse Practitioner | Complimentary |
| Physician Assistant | Complimentary |
| Other (Specify:__________________________________________) | Complimentary |








