| Volume
2 – General Questions About Hepatitis C (HCV) |
| September
10, 2004 |
What
are some of my options? Where can I find more information?
Your doctor will help
determine if the treatment medications are an option for you; however,
the final decision about whether to be treated is up to you.
If you decide to be
treated, you will first need a liver biopsy to find out how damaged your
liver is (the amount of scarring and inflammation). The liver biopsy is
relatively simple and is done as an outpatient procedure. We numb the
area where we will take the biopsy and use a long needle to take a very
small sliver of liver tissue that we then look at under the microscope.
If you decide not
to be treated, the doctor will follow you to make sure you and your liver
are not having any major problems.
There are many resources
for people who have hepatitis C. We hope this Website answers most of
your questions. The American
Liver Foundation is another resource for you to consider. Your doctor
should be able to provide you with literature about the disease.
How
sick will I become? What's going to happen to me?
It is very difficult
to predict what is going to happen. Usually we can "guesstimate"
if the disease is likely to progress faster or slower depending on how
long you have had it, how old you were at the time you became infected,
how much inflammation and fibrosis are present in your liver biopsy, whether
you are immunosuppressed or not, whether you have other liver inflammatory
conditions (such as chronic hepatitis B or fatty liver with inflammation),
whether you currently or have in the past used alcoholic beverages excessively,
and whether you are coinfected with HIV or not. Other factors such as
gender, weight, and ethnicity may also play a role but not a determining
one. It is important to remember that neither the viral genotype nor the
viral load are determinants of outcome of your disease and should not
be followed for that reason; on the other hand, these two are very strong
predictors of the outcome of therapy when interferon-based treatments
are used.
How
much of my liver is working? Can my liver repair itself?
We have no good way
of assessing how much of your liver is working. In chronic liver disease,
the liver usually can cope throughout years of continuous injury. Eventually,
it may reach a point where it cannot handle one or more of its functions,
entering the phase of decompensated liver disease. The liver is one of
the most resilient organs in our body; it actively repairs and remodels
itself, usually through years of continuous insult or damage. In rare
instances, the destruction of liver cells is so rapid and generalized
that it can overwhelm this ability of the liver to regenerate itself,
leading to acute liver failure. Hepatitis C almost never causes acute
liver failure.
When
will there be a cure for hepatitis C?
HCV is effectively cured in greater that 50% of the cases, depending on
which type of HCV you have-genotypes 1a, 1b, 2a, 2b, 3a, or 3b.
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