Hepatitis C Management

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Question:

I have had good experience with the use of DDB (biphenyl dimethyl bicarboxylate) 15 mg tds plus amantadine 100 mg bid in treating Egyptian patients with HCV (mostly type 4). They have had SVR of about 30% and stabilization of the condition chemically and pathologically in 90% of patients. What is your comment?

I have no experience with DDB but much experience with amantadine. Amantadine alone or in combination with interferon or in combination with peginterferon/ribavirin is not associated with significant gains in SVR.

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