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Biologic Therapies VI: Optimizing Therapies

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Cleveland Clinic R.J. Fasenmyer Center for Clinical Immunology presents the Biologic Therapies: Optimizing Therapies online series brings together world leaders in immune-based therapies and addresses cutting-edge translational immunology and the latest data on biologic therapeutics.

In the Biologic Therapies VI: Optimizing Therapies online series, an international, multi-disciplinary faculty of experts critically appraise recent basic laboratory breakthroughs in terms of their potential clinical implications and provide in-depth analyses of approved agents, new agents, predicting toxicity, clinical controversies, and new indications.

Monograph

Leonard Calabrese, DO
Biologic Therapies: Optimizing Therapies
Leonard Calabrese, DO; M. Elaine Husni, MD, MPH; Carmen Gota, MD; Bochra Jandali, MD; Jonathan Kay, MD; Elizabeth Kirchner, CNP; Gregg J. Silverman, MD
Estimated Time: 1 hour 30 minutes
Type: Monograph
Release Date: October 29, 2015
Expiration Date: October 29, 2017
Specialties: Rheumatology/Immunology; Internal Medicine & Subspecialties

Webcasts

Immunologic Plenary Session

Stanley Hazen, MD, PhD
Estimated Time: 30 minutes
Type: Webcast
Release Date: June 15, 2015
Expiration Date: June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Cardiology
Peter Lipsky, MD
Estimated Time: 45 minutes
Type: Webcast
Release Date: June 15, 2015
Expiration Date: June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology
Stefan Rose-John, PhD
IL6 in Health and Disease
Stefan Rose-John, PhD
Estimated Time: 30 minutes
Type: Webcast
Release Date: June 15, 2015
Expiration Date: June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology
Michael M. Lederman, MD
Estimated Time: 45 minutes
Type: Webcast
Release Date: June 15, 2015
Expiration Date: June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine

Starting And Stopping Treating To Target- What Do We Know?

Drs Cush and Kavanaugh
Estimated Time: 1 hour
Type: Webcast
Release Date: June 15, 2015
Expiration Date: June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine
Stanley Cohen, MD
Estimated Time: 30 minutes
Type: Webcast
Release Date: June 15, 2015
Expiration Date: June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology
Arthur Kavanaugh, MD
Estimated Time: 15 minutes
Type: Webcast
Release Date: June 19, 2015
Expiration Date: June 19, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Dermatology
Jonathan Kay, MD
Estimated Time: 30 minutes
Type: Webcast
Release Date: July 8, 2015
Expiration Date: July 8, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology, Oncology, Neurology

Bioengineering and Biosimilars

Gregg J. Silverman, MD
Estimated Time: 15 minutes
Type: Webcast
Release Date: June 24, 2015
Expiration Date: June 24, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology
Vibeke Strand, MD
Estimated Time: 15 minutes
Type: Webcast
Release Date: June 24, 2015
Expiration Date: June 24, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology, Oncology
Jonathan Kay, MD
Estimated Time: 15 minutes
Type: Webcast
Release Date: July 8, 2015
Expiration Date: July 8, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology, Oncology
Vibeke Strand, MD
Estimated Time: 15 minutes
Type: Webcast
Release Date: July 8, 2015
Expiration Date: July 8, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology, Oncology

Connective Tissue Diseases and Biologics 2015

Gregg J. Silverman, MD
Estimated Time: 15 minutes
Type: Webcast
Release Date: July 1, 2015
Expiration Date: July 1, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology
Brad H. Rovin, MD
Estimated Time: 30 minutes
Type: Webcast
Release Date: July 1, 2015
Expiration Date: July 1, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology
Xavier Mariette, MD, PhD
Estimated Time: 30 minutes
Type: Webcast
Release Date: July 10, 2015
Expiration Date: July 10, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties: Rheumatology, Internal Medicine, Gastroenterology, Dermatology
Stanley Cohen, MD
Estimated Time:  30 minutes
Type: Webcast
Release Date:  June 15, 2015
Expiration Date:  June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Dermatology, Gastroenterology

Vaccines and Biologics

Clifton O. Bingham III, MD
Current Status and Recommendations
Clifton O. Bingham III, MD
Estimated Time:  30 minutes
Type: Webcast
Release Date:  June 15, 2015
Expiration Date:  June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Dermatology, Gastroenterology, Infectious Disease
Leonard Calabrese, DO
Estimated Time:  15 minutes
Type: Webcast
Release Date:  June 15, 2015
Expiration Date:  June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Dermatology, Gastroenterology, Infectious Disease

Biologic Cross Fire – What Can We Learn From Each Other

Brian G. Feagan, MD
Biologics in IBD
Brian G. Feagan, MD
Estimated Time:  15 minutes
Type: Webcast
Release Date:  July 6, 2015
Expiration Date:  July 6, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Gastroenterology
Vamsidhar Velcheti, MD
Biologics in Cancer
Vamsidhar Velcheti, MD
Estimated Time:  15 minutes
Type: Webcast
Release Date:  June 19, 2015
Expiration Date:  June 19, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Oncology
Anthony Fernandez, MD, PhD
Biologics in Dermatology
Anthony Fernandez, MD, PhD
Estimated Time:  15 minutes
Type: Webcast
Release Date:  June 19, 2015
Expiration Date:  June 19, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Dermatology
Jeffrey Cohen, MD
Estimated Time:  30 minutes
Type: Webcast
Release Date:  June 15, 2015
Expiration Date:  June 15, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Neurology
Christopher Ritchlin, MD, MPH
Biologics in PsA and SpA
Christopher Ritchlin, MD, MPH
Estimated Time:  30 minutes
Type: Webcast
Release Date:  June 24, 2015
Expiration Date:  June 24, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Gastroenterology, Dermatology
Leonard Calabrese, DO
Estimated Time:  15 minutes
Type: Webcast
Release Date:  June 24, 2015
Expiration Date:  June 24, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Gastroenterology, Dermatology

Safety and Comorbidity

Xavier Mariette, MD, PhD
Estimated Time:  30 minutes
Type: Webcast
Release Date:  July 2, 2015
Expiration Date:  July 2, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Dermatology, Gastroenterology, Neurology, Oncology
M. Elaine Husni, MD, MPH
Estimated Time:  15 minutes
Type: Webcast
Release Date:  June 24, 2015
Expiration Date:  June 24, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Cardiology
John J. Cush, MD
Estimated Time:  30 minutes
Type: Webcast
Release Date:  June 24, 2015
Expiration Date:  June 24, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Infectious Disease

Special Diseases – Current and Future Prospects of Biologic Therapies

Andrew Zeft, MD
Estimated Time:  30 minutes
Type: Webcast
Release Date:  July 10, 2015
Expiration Date:  July 10, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Pediatrics
Chad Deal, MD
Estimated Time:  30 minutes
Type: Webcast
Release Date:  June 24, 2015
Expiration Date:  June 24, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Endocrinology
Carol Langford, MD, MHS
Biologics and Vasculitis
Carol Langford, MD, MHS
Estimated Time:  30 minutes
Type: Webcast
Release Date:  June 24, 2015
Expiration Date:  June 24, 2017
Technical Requirements: Flash Player or Silverlight or QuickTime
Specialties:  Rheumatology, Internal Medicine, Dermatology, Gastroenterology, Pulmonology, Neurology

Series Objectives

  1. Summarize the current knowledge of the biology and pathology of autoimmune and inflammatory disease.
  2. Describe the impact of bioengineering and biosimilars on biologic therapy efficacy, toxicity, and changing patterns of use.
  3. Critically appraise the "treat to target" philosophy and describe strategies to incorporate it into clinical practice.
  4. Summarize data on vaccine efficacy and safety and develop strategies to incorporate vaccines into clinical practice with the goal of enhancing the safety of biologic therapies.
  5. Describe the efficacy and safety of biologic therapies and emerging new agents for systemic lupus erythematosus, Sjögren's syndrome, osteoporosis, vasculitis, and other disorders.
  6. Critically assess clinical data on biologic use in the related specialties of dermatology, oncology, neurology, and gastroenterology; synthesize their insights on shared mechanisms and new pathways for different diseases to potential implications for rheumatology.
  7. Develop strategies for improving safety and increasing adherence when using biologics by appraising best practices of experts and engaging in interactive case discussions.

Target Audience

The online series is designed for rheumatologists, dermatologists, gastroenterologists, internal medicine physicians, and associated allied health practitioners, including nurse practitioners, nurses, physician assistants interested in or using biologic therapeutics for autoimmune and inflammatory disorders.

Activity Directors

Leonard H. Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
R.J. Fasenmyer Chair of Clinical Immunology
Theodore F. Classen DO Chair of Osteopathic Research and Education
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

M. Elaine Husni, MD, MPH
Director, Arthritis and Musculoskeletal Treatment Center
Vice Chair, Department of Rheumatic & Immunologic Diseases
Orthopaedic and Rheumatologic Institute
Cleveland Clinic
Cleveland, OH

This CME activity was produced by Cleveland Clinic Foundation Center for Continuing Education and
R.J. Fasenmyer Center for Clinical Immunology
.