Bone Marrow Failure
Syndromes

Optimizing Outcomes Worldwide
through Disease Understanding

This series was recorded during a live satellite symposium at the ASH Annual Meeting in December 2008. The goal of this series is to review the pathobiology of bone marrow disorders, describe the variations in disease patterns across global regions, and evaluate the rationale for therapies and their evidence-based, clinically relevant application. This educational activity is designed for medical oncologists, hematologists, clinical and translational researchers, and other physicians and allied healthcare professionals treating patients with hematologic malignancies. In addition, members of patient advocacy groups will benefit from this program.

Webcast (all presentations from satellite symposium)
	Bone Marrow Failure Syndromes: Optimizing Outcomes Worldwide through Disease Understanding
	Estimated Time: Release Date: February 28, 2009 Type: Webcast	Technical Requirements: Windows Media Expiration Date: February 28, 2011 Specialties: Hematology, Oncology
Podcasts (6 audio presentations with slides)
	Bone Marrow Failure Syndromes: Optimizing Outcomes Worldwide through Disease Understanding
	Estimated Time: Six activities, each about 30 minutes Release Date: February 28, 2009 Type: Podcast	Technical Requirements: iTunes/Quicktime   Expiration Date: February 28, 2011 Specialties: Hematology, Oncology

Series Objectives

1. Distinguish variations in bone marrow failure epidemiology and treatment approaches in different regions of the world.
2. Describe the molecular basis of bone marrow failure syndromes, including array-based disease characteristics.
3. Develop treatment strategies that target epigenetic and other pathobiologic bases for bone marrow failure disorders.
4. Formulate strategies to minimize transformation of bone marrow failure syndromes to acute myeloid leukemia.
5. Apply knowledge of treatment approaches for bone marrow failure syndrome to clinical practice.
6. Identify practical strategies to make clinical trial involvement available to patients.

Activity Director

Mikkael Sekeres, MD, MS
Associate Professor of Medicine
Taussig Cancer Institute
Cleveland Clinic
Cleveland Ohio