Accreditation

1.75 AMA PRA Category 1 Credit(s)™.

The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this educational activity for a maximum of 1.75 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

This activity may be submitted for American Osteopathic Association Continuing Medical Education credit in Category 2.

Target Audience

This activity will be directed to rheumatologists, gastroenterologists, dermatologists, pulmonologists, nurse practitioners, physician assistants, and other health care professionals interested in or using biologic therapeutics in autoimmune and inflammatory disorders.

Description

This activity was presented at the Cleveland Clinic Richard J. Fasenmyer Center of Clinical Immunology Biologic Therapies for Autoimmune and Inflammatory Disease States Summit. The reviewed advances in biologic therapies for autoimmune diseases.

Objectives

At the conclusion of this activity, the participant will be able to:

1. Describe indications for prescribing TNF-alpha inhibitors for juvenile idiopathic arthritis (JIA).
2. Recognize key safety information that prescribing health care professionals should be prepared to discuss with patients with JIA and their parents.
3. Discuss what is known about immunizations in JIA patients on DMARDs and biological DMARDs.
4. Describe  the complexities of defining biologic failure.
5. Identify issues related to TNF switching.
6. Explain the effectiveness of switching to non-anti-TNF biologics.
7. Describe biologic therapies for ankylosing spondylitis.

Activity Director

Leonard H. Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Vice Chairman
Department of Rheumatic and Immunologic Diseases
R.J. Fasenmyer Chair of Clinical Immunology

Faculty

Ferdinand Breedveld, MD
Edward Keystone, MD, FRCPC
Philip Mease, MD
Nora Singer, MD

Faculty Disclosure

In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they may have a relationship, which in the context of their presentation(s), could be perceived as a potential conflict of interest: