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| Estimated Time of Completion |
2 hours |
| Description |
This activity was presented at the Cleveland Clinic Richard J. Fasenmyer Center of Clinical Immunology Biologic Therapies for Autoimmune and Inflammatory Disease States Summit. The summit reviewed advances in biologic therapies for autoimmune diseases. |
| Target Audience |
This activity will be directed to rheumatologists, gastroenterologists, dermatologists, pulmonologists, nurse practitioners, physician assistants, and other health care professionals interested in or using biologic therapeutics in autoimmune and inflammatory disorders. |
| Objectives |
At the conclusion of this activity, the participant will be able to:
- Recognize the mechanisms by which TNF-alpha contributes to disease progression from fatty liver to steatohepatitis or NASH.
- List potential indications for use of Anti-TNF therapy in the treatment of patients with acute alcoholic hepatitis.
- Discuss anti-TNF therapy in patients with underlying viral hepatitis b or c: potential indications and toxicities.
|
| Accreditation |
The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.
The Cleveland Clinic Foundation Center for Continuing Education designates this educational activity for a maximum of 2.0 AMA PRA Category 1 Credit(s)™. Physicians should only claim credit commensurate with the extent of their participation in the activity.
Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association Council on Continuing Medical Education for Category 2 credit. |
| Activity Director |
Leonard H. Calabrese, DO
Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Vice Chairman
Department of Rheumatic & Immunologic Diseases
R.J. Fasenmyer Chair of Clinical Immunology |
| Faculty |
Ariel E. Feldstein, MD
Assistant Professor of Molecular Medicine
Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University
Department of Pediatric Gastroenterology and Cell Biology
Cleveland Clinic
Cleveland, Ohio |
Robert O'Shea, MD, MSCE
Professor of Medicine
Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University
Director, Hepatology Fellowship Program
Department of Gastroenterology & Hepatology
Cleveland Clinic
Cleveland, Ohio |
Nizar N. Zein, MD
Associate Professor of Medicine
Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University
Chief, Section of Hepatology
Medical Director, Liver Transplantation
Department of Gastroenterology & Hepatology
Cleveland Clinic
Cleveland, Ohio |
|
| Faculty Disclosure |
In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are free of commercial bias.
The following faculty have indicated that they may have a relationship, which in the context of their presentation(s), could be perceived as a potential conflict of interest:
| Leonard Calabrese, DO |
|
Consulting, Teaching and Speaking |
Genentech
|
| |
Teaching and Speaking |
Abbott; Amgen; Wyeth |
| |
| Nizar Zein, MD |
| |
Consulting
|
Valeant Pharmaceuticals
|
| |
Research |
Centerscope; Coley Pharmaceutical; Roche; Schering-Plough |
The following faculty have indicated that they have no relationship which, in the context of their presentations, could be perceived as a potential conflict of interest:
Ariel Feldstein, MD
Robert O’Shea, MD, MSCE |
The Cleveland Clinic Foundation Center for Continuing Education acknowledges
educational grants for partial support of this activity from:
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 |
 |
| Genentech and Biogen Idec. |
 |
 |
Gold Level
This CME activity was produced by The Cleveland Clinic Foundation
Center for Continuing Education and UNITECH Communications®.
CME Disclaimer
The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity. |
