Overview
The Cleveland Clinic International Epilepsy Summit is a comprehensive, multi-day summit bringing together leading experts and innovative thinkers to explore breakthroughs and best practices in pediatric epilepsy care. Bringing together international leaders in pediatric epilepsy, neurology, neurosurgery, genetics, and artificial intelligence, the summit provides an in-depth review of the global burden of pediatric epilepsy, advances in early diagnosis, and contemporary therapeutic strategies. The summit emphasizes precision diagnosis and individualized care, highlighting innovations in EEG, advanced imaging, invasive evaluation, medical management of drug-resistant epilepsy, dietary therapies, including neuromodulation, and emerging pharmacologic approaches.
A central focus of the summit is the evolution of pediatric epilepsy surgery and future-facing innovation, with extensive coverage of stereoelectroencephalography (SEEG), minimally invasive and SEEG-guided surgical techniques, and outcomes-driven patient selection. Additional sessions explore the rapidly expanding role of artificial intelligence in seizure prediction, EEG interpretation, and clinical decision making; advances in genetics and precision medicine; and next-generation therapies including brain–computer interfaces and integrated care models. Through expert lectures, panel discussions, and real-world clinical insights, this summit aims to equip clinicians with evidence-based strategies and practical tools to improve outcomes and advance care for children with epilepsy worldwide.
Target Audience
This educational activity is intended for adult and pediatric neurologists, neurosurgeons, pediatricians, emergency medicine, critical care, infectious disease, and primary care physicians, fellows, residents, psychologists, nurse practitioners, physician assistants, neuroscientists, molecular biologists, pathologists, and geneticists.
Learning Objectives
After completing this educational activity, participants will be able to do the following:
- Summarize the clinical impact of the global burden of pediatric epilepsy, recent diagnostic innovations, and advanced strategies for timely management.
- Describe the technical advances in diagnostic modalities for pediatric epilepsy, especially electroencephalogram and imaging studies, and discuss their implications on clinical care.
- Critically review current clinical strategies for treating drug-resistant pediatric epilepsy and epileptic encephalopathies, including neuromodulation, and dietary options
- Discuss the clinical impact of advances in pediatric epilepsy surgery, especially in stereoelectroencephalography (SEEG), as it relates to management strategies and eligible populations.
- Review recent innovations in SEEG-guided epilepsy surgery and describe their potential use in pediatric patients with epilepsy.
- Discuss the current state and future innovations in the next-generation of antiseizure medications and medical therapies.
- Describe future use of artificial intelligence (AI) to improve the detection, diagnosis, monitoring, and treatment of pediatric patients with epilepsy.
- Discuss the role of genetic testing, therapy, and targeted treatments in improving the accuracy of precision medicine for pediatric epilepsy.
- Summarize how advances in brain-computer interfaces, development of next-generation therapies, and integration of AI and genetics can influence care models in pediatric epilepsy.

