Journal CME

Volume 93, Number 1

Do corticosteroids prevent reactions to infusions of contrast, monoclonal antibodies, or chemotherapy?

How to Obtain AMA PRA Category 1 Credit™ and ABIM MOC points

  1. Review information on this page.
  2. Read the journal article.
  3. Return to this page and select the "Complete the CME/MOC Process" link.
  4. Login to your myCME account.
  5. If claiming MOC, choose the 'CME & MOC' option and complete the posttest.
  6. Complete the registration / evaluation form.
  7. Print your personalized CME / MOC certificate.

Release Date: January 1, 2026
Expiration Date: December 31, 2026

Estimated Time of Completion: 1 hour

Description

The authors examine the evidence and recommendations regarding prophylactic use of corticosteroids to prevent infusion-related reactions from radiographic contrast media, monoclonal antibodies, and cancer chemotherapeutic drugs.

Learning Objective

Recall recommendations regarding the utility of corticosteroid prophylaxis before infusions of radiographic contrast media, monoclonal antibodies, and cancer chemotherapeutic drugs.

Target Audience

Directed to practitioners in allergy/immunology, cardiology, hematology, and internal medicine, interventional radiology, oncology, radiology, rheumatology, and hospitalist.

ACCREDITATION STATEMENT

In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

CREDIT DESIGNATION

American Medical Association (AMA) 

Cleveland Clinic Foundation Center for Continuing Education designates this journal-based activity for a maximum of 1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Certificate of Participation 

A certificate of participation will be provided to other health care professionals for requesting credits in accordance with their professional boards and/or associations.

American Board of Internal Medicine (ABIM)

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.0 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

**Please Note** To receive MOC you must select the MOC option during the online credit claiming process and complete the required steps. ABIM MOC points will be reported within 30 days of claiming credit.

Activity Directors, Authors, and Other Contributors

Activity Director

Brian F. Mandell, MD, PhD
Chairman, Department of Academic Medicine, Education Institute,
Professor of Medicine, Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University,
Editor in Chief, Cleveland Clinic Journal of Medicine,
Cleveland Clinic, Cleveland, OH

Co-Activity Directors

Craig D. Nielsen, MD, FACP
Vice Chairman, Department of Internal Medicine;
Associate Professor, Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University, Cleveland, OH;
Governor, Ohio Chapter, American College of Physicians;
Deputy Editor, Cleveland Clinic Journal of Medicine,
Cleveland Clinic, Cleveland, OH

James C. Pile, MD
Department of Hospital Medicine;
Associate Professor, Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University, Cleveland, OH;
Deputy Editor, Cleveland Clinic Journal of Medicine,
Cleveland Clinic, Cleveland, OH

George Thomas, MD, MPH
Director, Center for Blood Pressure Disorders, Department of Kidney Medicine;
Associate Professor, Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University, Cleveland, OH;
Deputy Editor, Cleveland Clinic Journal of Medicine,
Cleveland Clinic, Cleveland, OH

Mary T. Cusick, MS
Executive Editor, Cleveland Clinic Journal of Medicine,
Cleveland Clinic, Cleveland, OH

Authors

Dylan T. Timberlake, MD
Department of Allergy and Clinical Immunology, Cleveland Clinic, Cleveland, OH;
Assistant Professor, Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University, Cleveland, OH

Sushmitha Boppana, MD
Department of Internal Medicine, Cleveland Clinic Akron General, Akron, OH

James Fernandez, MD, PhD
Department of Allergy and Clinical Immunology, Cleveland Clinic, Cleveland, OH;
Clinical Assistant Professor, Cleveland Clinic Lerner College of Medicine
of Case Western Reserve University, Cleveland, OH

Other Contributors

CME Disclaimer

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

Disclosures

In accordance with the Standards for Integrity and Independence issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Foundation Center for Continuing Education mitigates all relevant conflicts of interest to ensure CME activities are free of commercial bias.

The following faculty have indicated that they have a relationship which, in the context of their contributions, could be perceived as a potential conflict of interest:

Brian F. Mandell, MD, PhD (Activity Director)
  Consulting Amgen, Horizon Pharma
  Research: PI local site Amgen, Arthrosi Pharma
  Teaching and Speaking Arthrosi Pharma
  Advisor or review panel participant Arthrosi Pharma
  Data Monitoring Safety Board Wave Therapeutics
Adam J. Brown, MD
  Consulting Amgen, Sanofi
  Teaching and speaking Amgen, Sanofi
Abhijit Duggal, MD
  Advisor or review panel participant Alung Technologies
Yuebing Li, MD
  Research: Principal investigator Alexion, Argenx, Immunovant, Johnson & Johnson, Vertex Pharmaceuticals
  Member of Clinical Practice Scientific Advisory Board Alexion
  Consulting Argenx, Immunovant, Johnson & Johnson, Vertex Pharmaceuticals
Christian Nasr, MD
  Advisor or review panel participant Horizon Therapeutics, Viridian Therapeutics
James Fernandez, MD, PhD
  Teaching and speaking Baxalta

All other authors, co-activity directors, reviewers and CCJM staff report no relevant financial relationships which, in the context of their contributions, could be perceived as a potential conflict of interest.


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after completion, claim CME

This CME activity was produced by the Cleveland Clinic Journal of Medicine and the Cleveland Clinic Center for Continuing Education.