Advances in basic and translational immunology for the clinical rheumatologist

• Critically appraise and integrate clinical data on the efficacy and toxicity of CAR T-cell therapies, cellular therapies, and other advanced treatments, to identify and propose strategies that could lead to long-term remission or cure of immune-mediated inflammatory diseases.
• Evaluate the efficacy and safety of IL-17 inhibitors (e.g., secukinumab, ixekizumab) and IL-23 inhibitors (e.g., ustekinumab, guselkumab) in treating immune mediated inflammatory diseases, and assess the risks, including susceptibility to infections and the implications of long-term use.
• Explore and interpret the latest advances in IL-23 inhibitors for immune mediated inflammatory diseases, and assess their potential for treating other inflammatory conditions by examining emerging research and future clinical applications.

The online series is directed towards rheumatologists, allergists/immunologists, dermatologists, internal medicine physicians, nurse practitioners, nurses, and physician assistants interested in or using biologic therapeutics for autoimmune and autoinflammatory disorders.

In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Physicians / American Medical Association (AMA)
Cleveland Clinic Center for Continuing Education designates this internet enduring activity for a maximum of 2.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Nurses / American Nurses Credentialing Center (ANCC)
Cleveland Clinic Center for Continuing Education designates this internet enduring activity for a maximum of 2.75 ANCC contact hours.

Physician Assistants / American Academy of PAs (AAPA)
Cleveland Clinic Center for Continuing Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 2.75 AAPA Category 1 CME credits. PAs should only claim credit commensurate with the extent of their participation.

Certificate of Participation
A certificate of participation will be provided to other health care professionals for requesting credits in accordance with their professional boards and/or associations.

Activity Director

Leonard H. Calabrese, DO
R.J. Fasenmyer Chair of Clinical Immunology
Department of Rheumatic & Immunologic Diseases
Medical Specialty Institute
Cleveland Clinic
Cleveland, OH

Cassandra Calabrese, DO
Department of Rheumatic & Immunologic Diseases
Medical Specialty Institute
Cleveland Clinic
Cleveland, OH

M. Elaine Husni, MD, MPH
Director, Arthritis and Musculoskeletal Treatment Center
Vice Chair, Rheumatology
Department of Rheumatic & Immunologic Diseases
Medical Specialty Institute
Cleveland Clinic
Cleveland, OH

Additional Planners

Debra Kangisser, PA-C
Elizabeth (Betsy) Kirchner, DNP

Faculty

Maximilian F. Konig, MD
Assistant Professor of Medicine
Director, Cellular Therapy Program (Autoimmunity)
Division of Rheumatology, Department of Medicine,
The Johns Hopkins University School of Medicine
Baltimore, MD

Deepak Rao, MD, PhD
Associate Professor of Medicine
Co-Director, Center for Cellular Profiling
Brigham and Women’s Hospital
Harvard Medical School
Boston, MA

Christopher Ritchlin, MD, MPH
Director, Clinical Immunology Research Unit
University of Rochester Medicine
Rochester, NY

William Robinson, MD, PhD
Raitt Professor of Medicine
Stanford University
Palo Alto, CA

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.