Webcast CME

Cleveland Clinic Tall Rounds®: Caring for Your Patients with ATTR

Treating Confirmed ATTR

Release date: April 30, 2024
Expiration date:
April 29, 2026

Estimated Time of Completion: 1 hour


Early diagnosis and intervention for transthyretin amyloidosis (ATTR) is critical, yet does not occur, typically as a consequence of the rarity and heterogeneity of the disease and limited awareness on the part of clinicians. Therapeutic options are limited, but there are new and emerging agents and emerging indications with which clinicians may not be familiar. Access to specialized care centers is limited for many patients, leading to suboptimal management and disease monitoring. This education fills a significant need for healthcare team education to ensure all patients benefit from best-practices in recognizing, diagnosing, and managing amyloidosis. Learn More about the Cleveland Clinic Amyloidosis Center

Session Agenda

Moderator Introduction: Mazen Hanna, MD

Case Presentation: Arianne Clare C. Agdamag, MD

Management of Cardiac Involvement: Preethi William, MD

Treatment of ATTR Cardiac Amyloidosis

Stabilizer Therapy: Trejeeve Martyn, MD, MSc

Silencer Therapy: Andres Carmona Rubio, MD

Antibody Therapy: Mazen Hanna, MD

Treatment of AL Amyloidosis: Jack Khouri, MD

Learning Objectives

  • Providing overview of ATTR-CM and ATTR-PN treatment approaches to patients.
  • Utilizing best practices in amyloidosis care to establish treatment plan for patients with confirmed ATTR.
  • Corresponding clinical team members with their roles in the optimal management of ATTR

Target Audience

This online series is designed for physicians, allied health practitioners and students interested in complex cardiovascular and thoracic conditions and those who care for patients with ATTR.


In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation American Medical Association (AMA)
Cleveland Clinic Center for Continuing Education designates this internet enduring activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Certificate of Participation
A certificate of participation will be provided to other health care professionals for requesting credits in accordance with their professional boards and/or associations.

Activity Director and Faculty

CME Disclaimer

The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic. In no event will The Cleveland Clinic be liable for any decision made or action taken in reliance upon the information provided through this CME activity.


In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are Free of commercial bias.

The following faculty has indicated they have no relationship which, in the context of their presentation(s), could be perceived as a potential conflict of interest: Kathleen Breznai, Jeanna Sigmund, MSN, Arianne Clare Agdamag, MD, Andres E Carmona Rubio, MD, Preethi William, MBBS

The following faculty has indicated that they may have a relationship, which in the context of their presentation(s) could be perceived as a potential conflict of interest: Eric E Roselli, MD: Artivion - Consulting, Teaching and Speaking. Cook Medical - Teaching and Speaking. Cryolife, Inc. - Consulting. Terumo - Teaching and Speaking. W.L. Gore & Associates - Consulting. Medtronic - Consulting. Edwards Lifesciences - Teaching and Speaking. Abbott - Teaching and Speaking. LivaNova, PLC - Consulting, Teaching and Speaking. Mazen Hanna, MD: Pfizer - Advisor or review panel participant. Alexion - Advisor or review panel participant. Alnylam - Advisor or review panel participant. Akcea Therapeutics, Inc. - Advisor or review panel participant. Eidos Therapeutics - Advisor or review panel participant. Michael Trejeeve Martyn, MD: Recora Health - Consulting. Synkopi inc. - Consulting. Synkopi Inc. - Consulting. Recora Health - Consulting. Astra Zeneca - Research. Astra Zeneca - Research. Ionis Pharmaceuticals - Research. Ionis Pharmaceuticals -Research. Akcea Therapeutics, Inc. - Research. The Clinic by Cleveland Clinic - Consulting. The Clinic by Cleveland Clinic - Consulting. Fire1 - Consulting. Apricity Robotics - Consulting. Boehringer Ingelheim - Consulting. Jack Khouri, MD: GPCR Therapeutics - Teaching and Speaking, Research. Janssen Pharmaceuticals, Inc. - Consulting, Advisor or review panel participant.


The Cleveland Clinic Center for Continuing Education acknowledges educational grants for partial support of this activity from:

Alexion Pharmaceuticals, Inc.

Alnylam Pharmaceuticals, Inc.

AstraZeneca Pharmaceuticals

Please take before viewing this webcast

This CME activity was produced by the Cleveland Clinic Foundation Center for Continuing Education, The France Foundation, and Cleveland Clinic’s Heart, Vascular and Thoracic Institute.

For further information about this activity, contact Katie Breznai at [email protected]