Table 1: Evaluation of Prolonged PT or PTT

Table 1:
Evaluation of Prolonged PT or PTT
	Prolonged PT	Prolonged PTT	Prolonged PT and PTT
Inherited	Factor VII deficiency	VWF, VIII, IX, XI, or XII deficiency	Prothrombin, fibrinogen, V, X or combined factor deficiency
Acquired	Vitamin K deficiency Liver disease Warfarin use Factor VII inhibitor	Heparin Inhibitor of vWF, factors VIII, IX, XI, or XII Antiphospholipid antibody	Liver disease DIC Supratherapeutic heparin or Warfarin Combined heparin and Warfarin use Direct thrombin inhibitors Inhibitor of prothrombin, fibrinogen, or factor V or X