Agenda

Friday, December 5, 2025 All times in Eastern Time
7:00 am	Registration & Continental Breakfast
7:50 am	Welcome & Announcements Lars G. Svensson, MD, PhD
Session 1: A Contemporary Overview of Aortic Valve Disease in 2025 Moderators: Samir Kapadia, MD & Lars G. Svensson, MD, PhD
8:00 am	Contemporary trends in aortic valve disease management: Reflection on trial data & predictions for how the guidelines may evolve Samir Kapadia, MD
8:15 am	Valvular heart disease in women: Implication for aortic valve therapies Leslie Cho, MD
8:30 am	Evaluation of surgical & interventional risk: Key points for shared decision making Patrick T. O’Gara, MD
8:45 am	Case Presentation: Low-risk severe AS in a 55-year-old L. Leonardo Rodriguez, MD
9:00 am	Imaging cardiologist: Key clinical & multimodality imaging steps in work up & decision making Milind Desai, MD, MBA
9:10 am	Surgical role: Current data to justify SAVR Craig R. Smith, MD
9:20 am	Interventional: Current data to justify interventional, low risk TAVR trials: How do we use the new findings? Jeffrey J. Popma, MD
9:30 am	What happened to the patient: Panel discussion/Q&A
9:40 am	Break & Exhibits
Session 2: Difficult Scenarios in Aortic Valve Disease Part 1 Moderators: Marijan Koprivanac, MD & Amar Krishnaswamy, MD
10:00 am	Case Presentation: Stenotic bicuspid aortic valve in an octogenarian Christine Jellis, MD, PhD
10:05 am	Clinical Cardiologist: Assessing frailty & futility, multimodality imaging, concomitant aortopathy Milind Desai, MD, MBA
10:15 am	Interventional: Association of BAV anatomy with TAVR outcomes Samir Kapadia, MD
10:25 am	Surgeon: Role of surgery & contemporary outcomes Marijan Koprivanac, MD
10:35 am	What happened to the patient & Panel discussion/Q&A
10:45 am	Case Presentation: Low flow - low gradient AS Brian Griffin, MD
10:50 am	Cardiologist: (role of assessing flow reserve, aortic calcium scoring, small annulus, imaging/cath discordance) Image guidance technologies & the team approach to SHD interventions in the OR & Cath Lab L. Leonardo Rodriguez, MD
11:00 am	Interventional Cardiologist: Current state of the art data PLUS echo/cath discordance Grant Reed, MD
11:10 am	Surgeon: The benefit of surgical intervention in low flow, low gradient severe aortic stenosis Marijan Koprivanac, MD
11:20 am	What happened to the patient: Panel discussion/Q&A
Session 3: Aortic Valve Endocarditis Moderators: Leslie Cho, MD & Brian Griffin, MD
11:30 am	Case Presentation: Aortic valve endocarditis L. Leonardo Rodriguez, MD
11:35 am	Clinical/Imaging Cardiologist: Role of multimodality imaging & clinical work up Christine Jellis, MD, PhD
11:45 am	Critical care management of endocarditis Leslie Cho, MD
11:55 am	Surgeon: What surgical options would I consider? (Including Ozaki) Shinya Unai, MD
12:05 pm	What happened to the patient: Panel discussion/Q&A
12:15 pm	Break, Exhibits & Lunch Buffet
12:45 pm	Lunch Panel Discussion Moderator: Lars G. Svensson, MD, PhD Where we are & where we need to go Panel Participants: Samir Kapadia, MD, Patrick T. O’Gara, Jeffrey J. Popma, MD, Craig R. Smith, MD
Session 4: Difficult Scenarios in Aortic Valve Disease Part 2 Moderators: Christine Jellis, MD, MBA & L. Leonardo Rodriguez, MD
1:15 pm	Case Presentation: Radiation heart disease with aortic valve involvement Christine Jellis, MD, PhD
1:20 pm	Clinical Cardiologist: Diagnosis & management Milind Desai, MD, MBA
1:30 pm	Interventional options Amar Krishnaswamy, MD
1:40 pm	Surgical options including TAVR explant Shinya Unai, MD
1:50 pm	What happened to the patient: Panel discussion/Q&A
Session 4: Aortic Valve and Connective Tissue Disorders Moderators: Milind Desai, MD & Grant Reed, MD
2:00 pm	Case Presentation: Young patient with connective tissue disorder with enlarged aortic root: LDS vs. Marfan Syndrome Brian Griffin, MD
2:05 pm	Clinical/Imaging: Work up of these patients: Current guidelines Christine Jellis, MD, PhD
2:15 pm	Surgical management of the Aortic Root Lars G. Svensson, MD, PhD
2:25 pm	What happened to the patient: Panel discussion/Q&A
2:35 pm	Break & Exhibits
Session 5: Aortic Regurgitation in the Modern Era Moderators: Lars G. Svensson, MD, PhD & Brian Griffin, MD
2:55 pm	Case Presentation – Patient with severe AI Brian Griffin, MD
3:00 pm	Clinical/Imaging: Multimodality imaging work up & modern reappraisal of guidelines Milind Desai, MD MBA
3:10 pm	Intervention: Treatment of AI using TAVR systems Grant Reed, MD
3:20 pm	Surgeon: Aortic valve regurgitation including bicuspid valves: When to repair vs. Ross vs. replace with root management? Lars G. Svensson, MD, PhD
3:40 pm	What happened to the patient: Panel discussion/Q&A
Session 5: Management of Concomitant LVOT Obstruction (HOCM, subaortic membrane) Moderators: Shinya Unai, MD & Milind Desai, MD, MBA
3:50pm	Case Presentation – HOCM case with LVOT obstruction Milind Desai, MD, MBA
3:55pm	Cardiologist: Diagnosis & medical management Milind Desai, MD, MBA
4:05 pm	Surgeon: Myectomy & membrane resection with concomitant AV Shinya Unai, MD
4:15 pm	Interventional: Septal ablation (include suicide ventricle & need during interventional procedures) Amar Krishnaswamy, MD
4: 25 pm	What happened to the patient: Panel discussion/Q&A All session faculty
4:35 pm	Closing Comments & Adjourn Day 1

Saturday, December 6, 2025 All times in Eastern Time
7:00 am	Breakfast
7:50 am	Welcome & Introduction
Session 1: New Data in Aortic Valve Diagnosis & Management Over the Last Two Years Moderators: Samir Kapadia, MD & Grant Reed, MD
8:00 am	Most important TAVR papers 2024-24 (surgery versus TAVR data, bicuspid, EARLY TAVR type data, Moderate AS, Small annulus) Grant Reed, MD
8:10 am	My most important contributions to TAVR from CC 2024-25 Samir Kapadia, MD
8:20 am	The most important surgical aortic valve papers from Cleveland Clinic Marijan Koprivanac, MD
Session 2: The Crystal Ball: What will be the critical steps in management of aortic valve disease over next few years? Moderators: Amar Krishnaswamy, MD & Grant Reed, MD
8:30 am	Clinical information & management: Beyond the Index Procedure – Upstream & downstream therapies L. Leonardo Rodriguez, MD
8:40 am	Emerging medical therapies to slow progression of calcific AS Milind Desai, MD MBA
8:50 am	Interventional techniques & trials (include importance of pre-emptive TAVR in the future management of AS, device durability challenges) Jeffrey J. Popma, MD
9:00 am	Surgical trials & techniques Craig Smith, MD
9:10 am	Panel discussion/Q&A
9:20 am	Break & Exhibits
Session 3: Heart failure with AI and AS Moderators: Brian Griffin, MD & Christine Jellis, MD, PhD
9:45 am	Managing HF in AS with multivalve disease Brian Griffin, MD
9:55 am	Aortic stenosis & heart failure Amar Krishnaswamy, MD
10:05 am	Case Presentation: Cardiogenic shock presenting to CICU Christine Jellis, MD, PhD
10:10 am	Critical care cardiology assessment & decision making Leslie Cho, MD
10:20 am	Interventional: TAVR in cardiogenic shock Grant Reed, MD
10:30 am	Surgical: Any role for surgery or MCS? Marijan Koprivanac, MD
10:40 am	What happened to the patient: Panel discussion/Q&A
Session 4: Managing Post-interventional Issues – Rapid Fire Moderators: Brian Griffin, MD & L. Leonardo Rodriguez, MD
10:50 am	Importance of prosthesis-patient mismatch after TAVR: Definitions, incidence & clinical relevance L. Leonardo Rodriguez, MD
11:00 am	Planning for TAV-in-TAV: Technical considerations & long-term risks Amar Krishnaswamy, MD
11:10 am	Optimal anti-thrombotic therapy after TAVR: Updates & controversies Grant Reed, MD
11:20 am	Predictors of pacemaker dependency Samir Kapadia, MD
11:30 am	Management of hemodynamic collapse during TAVR management in Amar Krishnawamy, MD
11:40 pm	Cerebral embolic protection during TAVR: what does the data support? Samir Kapadia, MD
11:50 am	Management of paravalvular leaks after SAVR & TAVR Grant Reed, MD
12:00 pm	Panel discussion / Q&A
12:15 pm	Adjourn

Agenda

Friday, December 5, 2025
All times in Eastern Time

Session 1: A Contemporary Overview of Aortic Valve Disease in 2025
Moderators: Samir Kapadia, MD & Lars G. Svensson, MD, PhD

Session 2: Difficult Scenarios in Aortic Valve Disease Part 1
Moderators: Marijan Koprivanac, MD & Amar Krishnaswamy, MD

Session 3: Aortic Valve Endocarditis
Moderators: Leslie Cho, MD & Brian Griffin, MD

Session 4: Difficult Scenarios in Aortic Valve Disease Part 2
Moderators: Christine Jellis, MD, MBA & L. Leonardo Rodriguez, MD

Session 4: Aortic Valve and Connective Tissue Disorders
Moderators: Milind Desai, MD & Grant Reed, MD

Session 5: Aortic Regurgitation in the Modern Era
Moderators: Lars G. Svensson, MD, PhD & Brian Griffin, MD

Session 5: Management of Concomitant LVOT Obstruction (HOCM, subaortic membrane)
Moderators: Shinya Unai, MD & Milind Desai, MD, MBA

Saturday, December 6, 2025
All times in Eastern Time

Session 1: New Data in Aortic Valve Diagnosis & Management Over the Last Two Years
Moderators: Samir Kapadia, MD & Grant Reed, MD

Session 2: The Crystal Ball: What will be the critical steps in management of aortic valve disease over next few years?
Moderators: Amar Krishnaswamy, MD & Grant Reed, MD

Session 3: Heart failure with AI and AS
Moderators: Brian Griffin, MD & Christine Jellis, MD, PhD

Session 4: Managing Post-interventional Issues – Rapid Fire
Moderators: Brian Griffin, MD & L. Leonardo Rodriguez, MD

Agenda

Friday, December 5, 2025 All times in Eastern Time

Session 1: A Contemporary Overview of Aortic Valve Disease in 2025 Moderators: Samir Kapadia, MD & Lars G. Svensson, MD, PhD

Session 2: Difficult Scenarios in Aortic Valve Disease Part 1 Moderators: Marijan Koprivanac, MD & Amar Krishnaswamy, MD

Session 3: Aortic Valve Endocarditis Moderators: Leslie Cho, MD & Brian Griffin, MD

Session 4: Difficult Scenarios in Aortic Valve Disease Part 2 Moderators: Christine Jellis, MD, MBA & L. Leonardo Rodriguez, MD

Session 4: Aortic Valve and Connective Tissue Disorders Moderators: Milind Desai, MD & Grant Reed, MD

Session 5: Aortic Regurgitation in the Modern Era Moderators: Lars G. Svensson, MD, PhD & Brian Griffin, MD

Session 5: Management of Concomitant LVOT Obstruction (HOCM, subaortic membrane) Moderators: Shinya Unai, MD & Milind Desai, MD, MBA

Saturday, December 6, 2025 All times in Eastern Time

Session 1: New Data in Aortic Valve Diagnosis & Management Over the Last Two Years Moderators: Samir Kapadia, MD & Grant Reed, MD

Session 2: The Crystal Ball: What will be the critical steps in management of aortic valve disease over next few years? Moderators: Amar Krishnaswamy, MD & Grant Reed, MD

Session 3: Heart failure with AI and AS Moderators: Brian Griffin, MD & Christine Jellis, MD, PhD

Session 4: Managing Post-interventional Issues – Rapid Fire Moderators: Brian Griffin, MD & L. Leonardo Rodriguez, MD

Friday, December 5, 2025
All times in Eastern Time

Session 1: A Contemporary Overview of Aortic Valve Disease in 2025
Moderators: Samir Kapadia, MD & Lars G. Svensson, MD, PhD

Session 2: Difficult Scenarios in Aortic Valve Disease Part 1
Moderators: Marijan Koprivanac, MD & Amar Krishnaswamy, MD

Session 3: Aortic Valve Endocarditis
Moderators: Leslie Cho, MD & Brian Griffin, MD

Session 4: Difficult Scenarios in Aortic Valve Disease Part 2
Moderators: Christine Jellis, MD, MBA & L. Leonardo Rodriguez, MD

Session 4: Aortic Valve and Connective Tissue Disorders
Moderators: Milind Desai, MD & Grant Reed, MD

Session 5: Aortic Regurgitation in the Modern Era
Moderators: Lars G. Svensson, MD, PhD & Brian Griffin, MD

Session 5: Management of Concomitant LVOT Obstruction (HOCM, subaortic membrane)
Moderators: Shinya Unai, MD & Milind Desai, MD, MBA

Saturday, December 6, 2025
All times in Eastern Time

Session 1: New Data in Aortic Valve Diagnosis & Management Over the Last Two Years
Moderators: Samir Kapadia, MD & Grant Reed, MD

Session 2: The Crystal Ball: What will be the critical steps in management of aortic valve disease over next few years?
Moderators: Amar Krishnaswamy, MD & Grant Reed, MD

Session 3: Heart failure with AI and AS
Moderators: Brian Griffin, MD & Christine Jellis, MD, PhD

Session 4: Managing Post-interventional Issues – Rapid Fire
Moderators: Brian Griffin, MD & L. Leonardo Rodriguez, MD