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Course Information

Agenda

FRIDAY, AUG. 14
Moderator: Sobia Laique, MD
All times in Eastern Time

SESSION 1:
MASLD/MASH – Burden,Diagnosis, and Clinical Implications

7:00–8:00 AM
Breakfast / Exhibits
8:00–8:10 AM
Introduction to the Course
Sobia Laique, MD
8:10–8:30 AM
The Global Burden of MASLD: Epidemiology, Outcomes, and Health System Impact
Zobair Younossi, MD
8:30–8:50 AM
Screening, Risk Stratification, and Surveillance: Who Are We Missing?
Meena Bansal, MD
8:50–9:10 AM
Histopathology of MASH: What Still Requires Tissue, and Why It Matters
Daniela Allende, MD
9:10–9:30 AM
The Growing Burden of MASH Cirrhosis: Clinical Outcomes and Transplantation
9:30–10:00 AM
Panel Discussion:
From Population Risk to Cirrhosis: Where Are We Falling Short in MASLD/MASH Care?

Moderator: Sobia Laique, MD
Panelists: Daniela Allende, MD; Meena Bansal, MD;
Zobair Younossi, MD
10:00–10:30 AM
Break / Exhibits

SESSION 2:
Treatment of MASH Across the Disease Spectrum

10:30–10:50 AM
Incretin Therapy in MASH: Semaglutide and Related Agents
Keren Zhou, MD
10:50–11:10 AM
Disease-Modifying Therapy in MASH: Resmetirom and Emerging Strategies Across Fibrosis and Cirrhosis
Naim Alkhouri, MD
11:10–11:30 AM
Metabolic and Bariatric Surgery in MASH
Ali Aminian, MD
11:30–11:50 AM
Delivering MASH Care at Scale: The Multidisciplinary MASLD Clinic Model
Sobia Laique, MD
11:50 AM–12:10 PM
Cardio-Renal-Metabolic Risk in MASH
Luke Laffin, MD
12:10–12:30 PM
Sarcopenia and Frailty in MASH: Clinical Relevance and Management Considerations
Srinivasan Dasarathy, MD
12:30–1:00 PM
Panel Discussion: Precision Treatment in MASH: Matching Therapies to Patient Phenotypes
Moderator: Zobair Younossi, MD
Panelists: Naim Alkhouri, MD; Ali Aminian, MD; Srinivasan Dasarathy, MD; Luke Laffin, MD; Sobia Laique, MD; Keren Zhou, MD
1:00–2:00 PM
Lunch / Exhibits

SESSION 3:
Translational Science and Clinical Research in MASH

2:00–2:20 PM
Computational Approaches to MASH Pathophysiology and Drug Discovery
2:20–2:40 PM
Artificial Intelligence in MASH and Transplant Research: Risk Prediction, Drug Development, and Trial Design
Chase Wehrle, MD
2:40–3:00 PM
Clinical Trial Design in MASH: Endpoints, Populations, and Evolving Regulatory Expectations
Naim Alkhouri, MD
3:00–3:20 PM
Studying MASH in Cirrhosis: Pathobiology, Endpoints, and Research Challenges
Mary Rinella, MD
3:20–3:40 PM
Big Data and Transplantation: A New Age of Donor Assessment and Management
Kazunari Sasaki, MD
3:40–4:00 PM

Panel Discussion: The Future of MASH Research
Moderator: Sobia Laique, MD

Panelists: Naim Alkhouri, MD; Mary Rinella, MD; Kazunari Sasaki, MD; Chase Wehrle, MD

4:00 PM
Adjourn
4:30–6:30 PM
Networking Reception
(Non-CME/Optional)

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SATURDAY, AUG. 15
Moderator: Ali Aminian, MD
All times in Eastern Time

SESSION 4A:
Transplant Candidacy, Risk Stratification, and Outcomes in MASH

7:00–7:45 AM
Breakfast / Exhibits
7:45–8:00 AM
Welcome
Ali Aminian, MD
8:00–8:20 AM
Beyond MELD: Transplant Evaluation and Risk Stratification in MASH Cirrhosis
8:20–8:40 AM
Acute on Chronic Liver Failure in MASH: Prognosis, Optimization, Transplant Timing
Christina Lindenmeyer, MD
8:40–9:00 AM
Cardiac Risk Assessment in the MASH Transplant Candidate
Maan Fares, MD
9:00–9:20 AM
Metabolic Surgery and Liver Transplantation
Matthew Kroh, MD
9:20–9:40 AM
The Role of Living Donor Liver Transplantation in MASH
Julie Heimbach, MD
9:40–10:00 AM
Panel Discussion: Optimizing Transplant Candidacy and Outcomes in MASH
Moderators: Ali Aminian, MD and Koji Hashimoto, MD, PhD
Panelists: Maan Fares, MD; Julie Heimbach, MD; Matthew Kroh, MD
10:00–10:30 AM
Break / Exhibits

SESSION 4B:
Complex and Multi-Organ Transplant Decision-Making in MASH

10:30–10:50 AM
Liver Kidney Transplantation in MASH: Selection Criteria, Outcomes, and Allocation
Kazunari Sasaki, MD
10:50–11:10 AM
Modern Multi-Organ Transplant: Heart-Lung-Liver
Kenneth McCurry, MD
11:10–11:30 AM
Organ Preservation Strategies in High-Risk Liver Transplantation: Clinical Decision-Making
Andrea Schlegel, MD
11:30–11:50 AM
Robotic and Minimally Invasive Liver Transplantation: Current Indications and Outcomes
Alejandro Pita, MD
11:50 AM–12:00 PM
Panel Questions
Moderator: Koji Hashimoto, MD, PhD
Panelists: Kenneth McCurry, MD; Alejandro Pita, MD; Kazunari Sasaki, MD; Andrea Schlegel, MD
12:00–1:00 PM
Lunch / Exhibits

SESSION 5:
MASH and Cancer (HCC, CCA)

1:00–1:20 PM
Early Diagnosis, Staging, and Management of MASH Related Cancers: Hepatocellular Carcinoma and Cholangiocarcinoma
Shilpa Junna, MD
1:20–1:40 PM
Locoregional and Systemic Treatment Approaches for Liver Cancer
Suneel Kamath, MD
1:40–2:00 PM
Patient Selection for Liver Transplantation in MASH-Associated Liver Cancer
2:00–2:20 PM
Panel Discussion: Multidisciplinary Decision-Making in MASH-Associated Liver Cancer
Moderators: Mazhar Khalil, MD and Federico Aucejo, MD
Panelists: Julie Heimbach, MD; Shilpa Junna, MD; Suneel Kamath, MD
2:20 PM
Adjourn

NON-CME SESSION:
HANDS ON SYMPOSIUM

2:45–4:15 PM

Breakout 1:

Machine Perfusion in Liver Transplantation: HOPE, Normothermic Perfusion, and Regional Perfusion
Andrea Schlegel, MD; Koji Hashimoto, MD, PhD; Chase Wehrle, MD

 

Breakout 2:

Hands-On Fibrosis Assessment and Shared Medical Appointments in MASH
Sobia Laique, MD; Keren Zhou, MD

 

Breakout 3:

Bariatric and Metabolic Surgery in Patients with Liver Disease: Patient Selection and Pathways
Ali Aminian, MD; Salvador Navarrete, MD

 

Breakout 4:

Hands-On Minimally Invasive and Non-Invasive Therapies for Liver Tumors: Robotic Resection and Histotripsy
Mazhar Khalil, MD; Federico Aucejo, MD; Alejandro Pita, MD; Jaekeun Kim, MD

4:30–5:30 PM
Networking Reception
(Non-CME/Optional)

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