Release date:  June 10, 2025 
    Expiration date:  June 9, 2028  
    
Estimated Time of Completion:  1 hour 
 
		Description
        
			Each lesson in the Disease Management Clinical Decisions series provides a brief, case-based review of management strategies related to the topic. Questions and multiple-choice answers about the case presented include the rationale for the correct answer. Throughout this case-based lesson, you may proceed to the next question once you answer the question correctly.
				
			
	
		
Learning Objectives
	
	
	
  - Describe contemporary guidelines for starting low-dose  aspirin for the primary prevention of atherosclerotic cardiovascular disease. 
- Explain how low-dose aspirin guidance changes in  patients as they age.
- Critically appraise the use of low-dose aspirin among  patients with established cardiovascular disease and / or taking systemic  anticoagulation.
 
	 
 
	
		
Target Audience
	
	
	
		  Directed to primary care physicians including family practitioners and internists.  
  
 
	 
 
	
		
Accreditation
	
	
	
	  In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.
		
American  Medical Association (AMA)
  Cleveland  Clinic Center for Continuing Education designates this enduring activity for a  maximum of 1.0 AMA  PRA Category 1 Credits™. Physicians should claim only the credit  commensurate with the extent of their participation in the activity.
Participants claiming CME credit from this  activity may submit the credit hours to the American Osteopathic Association  for Category 2 credit.
ABIM MOC:  Successful  completion of this CME activity, which includes participation in the evaluation  component, enables the participant to earn up to 1.0 Medical Knowledge MOC points in the  American Board of Internal Medicine's (ABIM) Maintenance of Certification (MOC)  program. It is the CME activity provider's responsibility to submit participant  completion information to ACCME for the purpose of granting ABIM MOC credit.
  Your  credit will be reported to the ABIM within 30 days of claiming credit.  
ABS MOC: Successful completion of this CME activity, enables  the learner to earn credit toward the CME requirement(s) of the American Board  of Surgery’s Continuous Certification program. It is the CME activity  provider's responsibility to submit learner completion information to ACCME for  the purpose of granting ABS credit.
ABA MOC: This activity contributes to the CME component of  the American Board of Anesthesiology’s redesigned Maintenance of Certification  in AnesthesiologyTM (MOCA®) program, known as MOCA 2.0®. Please consult the ABA  website, www.theABA.org, for a list of all MOCA 2.0 requirements.
     
	 
 
	
		
Activity Director and Faculty
	
	
	
Activity  Directors
Anthony Fernandez, MD, PhD
  Director,  Medical and Inpatient Dermatology
  W.D. Steck  Chair of Clinical Dermatology
  Co-Director,  Center for Continuing Education
  Cleveland  Clinic
Cleveland,  OH
Steven Kawczak, PhD, CHCP, FACEHP
  Assistant  Professor of Medicine, Cleveland Clinic Lerner College of Medicine of CWRU
  Co-Director,  Center for Continuing Education 
  Director, Center for International  Medical Education
  Staff,  Center for Educational Resources 
  Education Institute 
  Cleveland  Clinic
  Cleveland,  OH
Faculty
  
Luke J. Laffin MD
  Co-Director, Center for Blood  Pressure Disorders
  Department of Cardiovascular  Medicine
  Cleveland Clinic
  Cleveland, OH
Carolina Pires Zingano, MD
  Cleveland Clinic
Cleveland, OH 
 
 
	 
 
	
		
CME Disclaimer
	
	
	
    	The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.
	 
	 
 
Disclosures
In accordance with the Standards for Integrity and Independence issued by the Accreditation Council for Continuing Medical Education (ACCME), Cleveland Clinic Center for Continuing 
Education mitigates all relevant conflicts of interest to ensure CME activities are free of commercial bias.
The following faculty have indicated that they may have a relationship, which in the context of their presentation(s), could be perceived as a potential conflict of interest:
				
 
  
    | Anthony P Fernandez,    MD, PhD | 
  
    | Biogen Inc., Boehringer      Ingelheim, UCB, Inc. | Consulting | 
  
    | Bristol-Myers      Squibb Co., Mallinckrodt Inc., Novartis | Consulting Teaching and Speaking
 | 
  
    | Pfizer, Inc. | Other      activities from which remuneration is received or expected: awarded a grant      to fund a medical dermatology fellowship position Research: PI
 | 
  
    | Alexion,      Castle Biosciences | Research:      Principal Investigator | 
  
    | Abbvie      Pharmaceuticals | Consulting Advisor or review panel participant
 Teaching and Speaking
 | 
  
    | Kyowa Kirin | Teaching and      Speaking | 
  
    | Luke J. Laffin,    MD | 
  
    | Astrazeneca Pharmaceuticals | Research (Ended: 12/31/2024) | 
  
    | Arrowhead, Crisper Therapeutics, Eli Lilly, Mineralys      Therapeutics | Research | 
  
    | Medtronic | Consulting | 
  
    | Idorsia Pharmaceuticals Ltd. | Consulting (Ended: 12/31/2024) | 
  
    | ReCor Medical | Consulting Teaching and Speaking
 | 
  
    | Cardiometabolic Health Congress | Teaching and Speaking (Ended: 12/31/2024) | 
  
    | Gordy Health | Advisor or review panel participant (Ended: 07/01/2024) | 
  
    | LucidAct Health | Advisor or review panel participant (Ended: 12/31/2024) | 
	
				
	All other persons in control of content have no relevant financial relationships.	
		
 		
				
This CME activity was produced by The Cleveland Clinic Foundation Center for Continuing Education.