4th Annual International PTEN Symposium: From Patient-Centered Research to Clinical Care

Monday, March 15, 2021

Course Description


This program, presented by Cleveland Clinic’s Genomic Medicine Institute and Center for Personalized Genetic Healthcare, will provide the opportunity to review the latest advances in PTEN hamartoma tumor syndrome (PHTS) and offer state-of-the-art information to healthcare providers treating patients with germline PTEN mutations. Expert Cleveland Clinic and guest faculty will share case-based presentations and research highlighting the advances of genetics and genomics of PHTS and the science of PTEN.

This program is endorsed by the PTEN Hamartoma Tumor Syndrome Foundation and PTEN Italia.

Target Audience

We invite practitioners and healthcare professionals seeking to learn the latest developments in PTEN management and research, especially providers in Oncology, Internal Medicine and Subspecialties, Pediatrics, Neurology, Dermatology, Endocrinology, Gastroenterology, Medical Genetics, Genetic Counseling, Nephrology, Urology, Women’s Health and Psychology/Psychiatry. Additionally, trainees and students with an interest in expanding their knowledge of PHTS and the science of PTEN are encouraged to attend. Patients, families and caregivers are also invited to attend to learn about cutting-edge PTEN research as well as clinical surveillance and management guidelines.


  • Describe current PTEN translational and clinical research
  • Apply research information about PHTS to diagnosis, screening, surveillance, guidelines, patient needs, clinical features and coordination of multidisciplinary team care
  • Demonstrate awareness and share education about PHTS, leading to timely diagnosis, appropriate surveillance and improved patient outcomes


The Cleveland Clinic Foundation Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

The Cleveland Clinic Foundation Center for Continuing Education designates this internet live activity for a maximum of 7.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Other Health Care Professionals

A certificate of participation will be provided to other health care professionals for requesting credits in accordance with state nursing boards, specialty societies, or other professional associations.

Evaluation and How to Obtain your AMA PRA Category 1 Credit(s)™ Certificate/Certificate of Participation

The ability to claim CME credit will be available on Monday, March 22. You have until April 20, 2021 to claim credit.

  1. Go to www.ccfcme.org/cmelogin to begin the activity evaluation and print your certificate.
  2. New Users: By attending this activity, an account has been created for you. Please follow these steps:
    • Click on ‘Reset Password.’
    • Enter email address used for registration.
    • Click on ‘Request Password Reset.’
    • You will receive an email to reset your password.
    Existing Users:
    • Enter email address used for registration.
    • Enter password.
  3. Select Complete Evaluation and complete all questions. Select the number of credits you are claiming by either using
    1. the drop-down OR
    2. checking the box marked ‘maximum available.’
  4. Click ‘Save and View Certificate.’
    Your official certificate will be displayed. Please print and keep with your permanent files. You may also access your account at any time to view and/or print CME certificates and transcripts.

** If you need assistance, contact the CME office at 216.444.9990 or myCME@ccf.org.

Virtual Exhibits

Please visit our virtual exhibits located on the website.


The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition. The viewpoints expressed in this CME activity are those of the faculty. They do not represent an endorsement by The Cleveland Clinic Foundation. In no event will The Cleveland Clinic Foundation be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

Recording or reproducing this event in any format is prohibited.

Copyright © 2021 The Cleveland Clinic Foundation. All Rights Reserved.


Funding for this conference was made possible (in part) by 1 R13 TR 003732 – 01 from the National Center for Advancing Translational Sciences (NCATS). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.